TcCLB.506945.160

S-adenosylmethionine synthetase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100388 OG7: OG7_0003674 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510053.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.506529.430 ⚠
alanine aminotransferase, putative, glutamic-
— Both
TcCLB.506605.170
inosine-guanine nucleoside hydrolase, putativ
— Both
TcCLB.511067.30 ⚠
transketolase, putative
— Both
TcCLB.506885.413 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— +1 more Both
TcCLB.511579.9 ⚠
fatty acyl CoA syntetase 1, putative (fragmen
— Both
TcCLB.508277.150
proliferative cell nuclear antigen (PCNA), pu
— Both
TcCLB.511581.10 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcCLB.506829.110 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcCLB.511581.20 ⚠
fatty acyl CoA syntetase 1 (fragment)
— Both
TcCLB.506829.100 ⚠
fatty acyl CoA syntetase 1, putative
— Both
TcCLB.508277.160 ⚠
glutaminyl-tRNA synthetase, putative
— Both
TcCLB.506529.420 ⚠
glutamic--pyruvic transaminase, putative, ala
— Both
TcCLB.511069.4 ⚠
transketolase, putative
— Both
TcCLB.503575.50 ⚠
fatty acyl CoA synthetase, putative
— Both
TcCLB.507257.60 ⚠
Fumarate hydratase class I, cytosolic
— Both
TcCLB.507669.10 ⚠
fumarate hydratase, putative
— Both
TcCLB.506529.508
glucose-6-phosphate isomerase, glycosomal, pu
— Both
TcCLB.507993.390
pyruvate kinase 2, putative
— Both
TcCLB.506107.20 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511731.60 ⚠
glutamyl-tRNA synthetase, putative
— OG7
TcCLB.511751.30 ⚠
queuine tRNA-ribosyltransferase, putative
— OG7
TcCLB.418069.10 ⚠
heat shock protein 70 (hsp70), putative (frag
— OG6
TcCLB.506943.4 ⚠
aldehyde dehydrogenase, putative
— Both
TcCLB.511733.10 ⚠
aldehyde dehydrogenase, putative
— Both
TcCLB.461165.16 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.506943.50 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcCLB.508537.10 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.510105.230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.506943.60 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcCLB.506409.240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, C-t
— Both
TcCLB.507811.114 ⚠
hypothetical protein, conserved
— Both
TcCLB.506367.10 ⚠
isovaleryl-coA dehydrogenase, putative (fragm
— Both
TcCLB.509829.20 ⚠
isovaleryl-coA dehydrogenase, putative
— Both
TcCLB.508731.60
adenylosuccinate synthetase, putative
— Both
TcCLB.506135.9 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcCLB.511211.160 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— Both
TcCLB.511211.170 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.509543.50 ⚠
DNAK protein, putative
— OG6
TcCLB.508813.15 ⚠
heat shock protein 70, putative (fragment)
— OG6
TcCLB.506777.60
NGG1 interacting factor 3, putative
— Both
TcCLB.504507.5 ⚠
trypanothione reductase, putative (fragment)
— Both
TcCLB.484299.10 ⚠
trypanothione reductase, putative
— Both
TcCLB.509167.100
valyl-tRNA synthetase, putative
— Both
TcCLB.504431.100
guanine deaminase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.