TcCLB.508813.15

heat shock protein 70, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100083 OG7: OG7_0000779 139 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 139 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.418069.10 ⚠
heat shock protein 70 (hsp70), putative (frag
— +1 more OG6
TcCLB.506135.9 ⚠
heat shock 70 kDa protein, putative (fragment
— +1 more OG6
TcCLB.511211.160 ⚠
heat shock protein 70 (hsp70), putative
— +1 more OG6
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— +1 more OG6
TcCLB.511211.170 ⚠
heat shock protein 70 (hsp70), putative
— +1 more OG6
TcCLB.509543.50 ⚠
DNAK protein, putative
— +1 more OG6
TcCLB.511745.10 ⚠
heat shock 70 kDa protein, mitochondrial prec
— +2 more OG6
TcCLB.506941.280 ⚠
heat shock 70 kDa protein, mitochondrial prec
— +2 more OG6
TcCLB.511585.40 ⚠
DNA-damage inducible protein DDI1-like protei
— OG6
TcCLB.506869.60 ⚠
protein kinase PK4, putative
— OG6
TcCLB.507925.69 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511559.20 ⚠
Uncharacterised protein family (UPF0160), put
— OG6
TcCLB.511527.82 ⚠
hypothetical protein, conserved
— OG6
TcCLB.447925.10 ⚠
cystathionine beta-synthase, putative (fragme
— OG6
TcCLB.508781.20 ⚠
ATP synthase, putative
— OG6
TcCLB.510143.24 ⚠
Hsc70-interacting protein (Hip), putative
— OG6
TcCLB.509149.9 ⚠
cystathionine beta-synthase, serine sulfhydry
— OG6
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG6
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG6
TcCLB.504431.100 ⚠
guanine deaminase, putative
— OG6
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506733.60 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG6
TcCLB.510215.10 ⚠
NADH-dependent fumarate reductase, putative
— OG6
TcCLB.509761.10 ⚠
Metallopeptidase family M24/FACT complex subu
— OG6
TcCLB.510957.9 ⚠
calpain-like cysteine peptidase, putative
— OG6
TcCLB.506563.190 ⚠
calpain-like cysteine peptidase, putative
— OG6
TcCLB.508463.29 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG6
TcCLB.508241.149 ⚠
cystathionine beta-synthase, putative (fragme
— OG6
TcCLB.508241.140 ⚠
serine sulfhydrylase, cysteine synthase, cyst
— OG6
TcCLB.507165.50 ⚠
cysteine synthase, putative
— OG6
TcCLB.503467.9 ⚠
NADH-dependent fumarate reductase, putative (
— OG6
TcCLB.510381.10 ⚠
cystathionine beta-synthase, putative
— OG6
TcCLB.508539.30 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511691.10 ⚠
cysteine synthase, cystathionine beta-synthas
— OG6
TcCLB.507993.280 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG6
TcCLB.509007.20 ⚠
hypothetical protein, conserved
— OG6
TcCLB.503841.80 ⚠
NADH-dependent fumarate reductase, putative
— OG6
TcCLB.439653.10 ⚠
NADH-dependent fumarate reductase, putative
— OG6
TcCLB.503855.40 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TcCLB.509805.210 ⚠
hypothetical protein, conserved
— OG6
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG6
TcCLB.507641.300 ⚠
groELprotein, chaperonin HSP60, mitochondrial
— OG6
TcCLB.511067.10 ⚠
tubulin folding cofactor D, putative
— OG6
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG6
TcCLB.509099.50 ⚠
trypanothione synthetase
— OG6
TcCLB.506857.110 ⚠
Uncharacterised protein family UPF0066, putat
— OG6
TcCLB.507641.290 ⚠
heat shock protein 60, chaperonin HSP60, mito
— OG6
TcCLB.507671.30 ⚠
25 kDa translation elongation factor 1-beta
— OG6
TcCLB.509445.10 ⚠
tryparedoxin peroxidase, putative
— OG6
TcCLB.507641.280 ⚠
chaperonin HSP60, mitochondrial precursor, gr
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.