TcCLB.507641.300

groELprotein, chaperonin HSP60, mitochondrial precursor, heat shock protein 60
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100393 OG7: OG7_0003335 38 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 38 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509233.180 ⚠
ATP synthase subunit beta, mitochondrial, put
— Both
TcCLB.511393.88 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.511211.160 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.506941.280 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— OG6
TcCLB.511211.170 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.508647.110 ⚠
Archaic Translocase of outer membrane 14 kDa
— Both
TcCLB.511555.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.511745.10 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TcCLB.509543.50 ⚠
DNAK protein, putative
— OG6
TcCLB.506135.9 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcCLB.510323.40 ⚠
heat shock protein 20, putative
— Both
TcCLB.508813.15 ⚠
heat shock protein 70, putative (fragment)
— OG6
TcCLB.506925.14 ⚠
hypothetical protein, conserved
— Both
TcCLB.506503.69 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcCLB.507883.100 ⚠
malate dehydrogenase, putative
— OG7
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.507639.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510431.120 ⚠
hypothetical protein, conserved
— Both
TcCLB.511115.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.506737.60 ⚠
hypothetical protein, conserved
— Both
TcCLB.506513.180 ⚠
hypothetical protein, conserved
— Both
TcCLB.504643.30 ⚠
ubiquitin-conjugating enzyme E2, putative
— Both
TcCLB.510431.20 ⚠
Ankyrin repeats (3 copies), putative
— Both
TcCLB.506647.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.483623.10 ⚠
Ankyrin repeats (3 copies), putative
— Both
TcCLB.503959.60 ⚠
START domain containing protein, putative
— Both
TcCLB.511589.150 ⚠
hypothetical protein, conserved
— Both
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.511445.90 ⚠
Domain of unknown function (DUF4470)/Domain o
— Both
TcCLB.507883.109 ⚠
mitochondrial malate dehydrogenase, putative
— Both
TcCLB.511751.70 ⚠
microtubule associated protein xmap215
— Both
TcCLB.510101.130 ⚠
inositol-1,4,5-trisphosphate (IP3) 5-phosphat
— Both
TcCLB.511395.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.506755.250 ⚠
inner membrane preprotein translocase Tim17,
— Both
TcCLB.418069.10 ⚠
heat shock protein 70 (hsp70), putative (frag
— OG6
TcCLB.509443.20 ⚠
mitochondrial RNA binding protein 1, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.