TcCLB.511751.70

microtubule associated protein xmap215
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101795 OG7: OG7_0005125 78 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 78 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507077.40
p21-C-terminal region-binding protein, putati
— Both
TcCLB.507831.110 ⚠
pumilio/PUF RNA binding protein 2, putative
— OG7
TcCLB.510073.30 ⚠
pumilio/PUF RNA binding protein 4, putative
— OG7
TcCLB.508787.30 ⚠
pumilio/PUF RNA binding protein 3, putative
— OG7
TcCLB.507521.110 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
TcCLB.397937.10 ⚠
pumilio/PUF RNA binding protein 1, putative
— OG7
TcCLB.510349.30
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504153.140
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.509803.40
5-oxoprolinase, putative
— Both
TcCLB.509759.19 ⚠
pumilio/PUF RNA binding protein 1, putative
— OG7
TcCLB.480997.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506237.19 ⚠
hypothetical protein, conserved
— OG6
TcCLB.507809.110
WD domain, G-beta repeat, putative
— Both
TcCLB.509769.30
Inositol hexakisphosphate, putative
— Both
TcCLB.503653.20
hypothetical protein, conserved
— Both
TcCLB.510101.250
hypothetical protein, conserved
— Both
TcCLB.510165.30 ⚠
R3H domain containing protein, putative
— Both
TcCLB.509805.130
bifunctional aminoacyl-tRNA synthetase, putat
— Both
TcCLB.506933.60 ⚠
mitochondrial RNA binding protein, putative
— Both
TcCLB.430539.10 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcCLB.509007.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511735.10 ⚠
chaperonin HSP60/CNP60, putative
— OG7
TcCLB.511733.130 ⚠
chaperonin HSP60, putative (fragment)
— OG7
TcCLB.510105.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507797.9 ⚠
nuclear transcription factor, putative
— OG7
TcCLB.507639.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.511735.79 ⚠
Translation machinery associated TMA7, putati
— OG7
TcCLB.510101.210
PUB domain containing protein, putative
— Both
TcCLB.511737.9 ⚠
Translation machinery associated TMA7, putati
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.508557.29 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508465.60
hypothetical protein, conserved
— OG7
TcCLB.506563.10 ⚠
pumilio/PUF RNA binding protein 9, putative
— OG7
TcCLB.510125.10 ⚠
pumilio/PUF RNA binding protein 6, putative
— OG7
TcCLB.507747.220 ⚠
protein farnesyltransferase, putative
— Both
TcCLB.509157.279 ⚠
Chaperonin HSP60, mitochondrial
— Both
TcCLB.506513.180
hypothetical protein, conserved
— Both
TcCLB.506755.279
hypothetical protein, conserved
— Both
TcCLB.508183.4
aspartyl aminopeptidase, putative (fragment)
— Both
TcCLB.508277.65
hypothetical protein, conserved
— Both
TcCLB.511351.9 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcCLB.507211.40 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcCLB.506519.130 ⚠
GMP reductase
— OG6
TcCLB.509127.70
Nop14-like family, putative
— Both
TcCLB.504643.30
ubiquitin-conjugating enzyme E2, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.