TcCLB.509805.130

bifunctional aminoacyl-tRNA synthetase, putative, prolyl-tRNA synthetase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100749 OG7: OG7_0002333 175 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 175 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511067.10
tubulin folding cofactor D, putative
— +2 more Both
TcCLB.506859.70
guide RNA associated protein, GAP2, putative
— Both
TcCLB.507537.30 ⚠
cysteinyl-tRNA synthetase, putative
— +2 more Both
TcCLB.506531.60 ⚠
hypothetical protein, conserved
— +2 more Both
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— Both
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.509805.210
hypothetical protein, conserved
— Both
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— Both
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.508647.40 ⚠
replication factor C, subunit 1, putative
— Both
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— Both
TcCLB.507711.320
DNA mismatch repair protein MSH2, putative
— Both
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— Both
TcCLB.504935.10 ⚠
Eukaryotic translation initiation factor 4E-4
— Both
TcCLB.506375.80
hypothetical protein, conserved
— Both
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcCLB.506135.70
hypothetical protein, conserved
— Both
TcCLB.480997.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511577.50
endo-beta-N-acetylglucosaminidase, putative
— Both
TcCLB.511111.10
translation initiation factor IF-2, putative
— Both
TcCLB.511351.9 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcCLB.506885.380
hypothetical protein, conserved
— Both
TcCLB.511585.40
DNA-damage inducible protein DDI1-like protei
— Both
TcCLB.510101.250
hypothetical protein, conserved
— Both
TcCLB.503653.20
hypothetical protein, conserved
— Both
TcCLB.506857.110
Uncharacterised protein family UPF0066, putat
— Both
TcCLB.509007.20
hypothetical protein, conserved
— Both
TcCLB.506733.60
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
TcCLB.507809.110
WD domain, G-beta repeat, putative
— Both
TcCLB.506529.590 ⚠
Centrosomal protein of 164 kDa, putative
— Both
TcCLB.507925.69
hypothetical protein, conserved
— Both
TcCLB.509803.40
5-oxoprolinase, putative
— Both
TcCLB.507993.280 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— Both
TcCLB.511545.140 ⚠
hypothetical protein, conserved
— OG6
TcCLB.503893.140 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.504203.50 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.508387.30 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.504153.140
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.507797.9 ⚠
nuclear transcription factor, putative
— OG7
TcCLB.506517.100 ⚠
ATPase family associated with various cellula
— OG7
TcCLB.511741.30 ⚠
replication factor C, subunit 2, putative
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.