TcCLB.506529.590

Centrosomal protein of 164 kDa, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_155789 OG7: OG7_0006042 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511133.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.508145.49 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507011.60 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.504029.101 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504431.30 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506127.170 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcCLB.509965.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506147.30 ⚠
synaptojanin (N-terminal domain), putative, i
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.504009.40 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcCLB.511143.12 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcCLB.508465.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511741.30 ⚠
replication factor C, subunit 2, putative
— OG7
TcCLB.506517.100 ⚠
ATPase family associated with various cellula
— OG7
TcCLB.507797.9 ⚠
nuclear transcription factor, putative
— OG7
TcCLB.508647.210 ⚠
dynein arm light chain, putative
— OG7
TcCLB.509153.110 ⚠
hypothetical protein
— OG7
TcCLB.510105.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.510859.50 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.510861.14 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.508675.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509825.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508179.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510101.160 ⚠
HIT zinc finger, putative
— OG7
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— OG7
TcCLB.486901.10 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TcCLB.511115.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509967.170 ⚠
dynein arm light chain, putative
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.506625.60 ⚠
inositol 5-phosphatase 1, putative
— OG7
TcCLB.510761.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507639.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511211.150 ⚠
gamma-tubulin complex component 3
— OG7
TcCLB.509805.130 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
TcCLB.510165.30 ⚠
R3H domain containing protein, putative
— Both
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— Both
TcCLB.508347.159 ⚠
microtubule-associated protein, putative, (fr
— Both
TcCLB.504427.130 ⚠
5'-3' exoribonuclease C, putative
— Both
TcCLB.506223.110 ⚠
Microtubule-binding protein MIP-T3, putative
— Both
TcCLB.504153.260 ⚠
Flagellum attachment zone protein 12
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.