TcCLB.506249.20

protein transport protein Sec23A, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100992 OG7: OG7_0004996 133 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 133 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506885.380 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510101.210 ⚠
PUB domain containing protein, putative
— OG7
TcCLB.509551.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.421959.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.464807.20 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcCLB.508183.4 ⚠
aspartyl aminopeptidase, putative (fragment)
— OG7
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.507927.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506529.590 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcCLB.506135.90 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.506135.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508041.60 ⚠
eukaryotic release factor 3, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.504153.260 ⚠
Flagellum attachment zone protein 12
— OG7
TcCLB.504427.130 ⚠
5'-3' exoribonuclease C, putative
— OG7
TcCLB.506857.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.507537.30 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.510165.30 ⚠
R3H domain containing protein, putative
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511305.20 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcCLB.506503.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.511577.50 ⚠
endo-beta-N-acetylglucosaminidase, putative
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.511111.10 ⚠
translation initiation factor IF-2, putative
— OG7
TcCLB.511555.80 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcCLB.510313.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.510747.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510861.14 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.510859.50 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.508277.140 ⚠
phosphomevalonate kinase protein, putative
— OG7
TcCLB.510105.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.468941.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.507809.110 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.504153.180 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
TcCLB.506755.279 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509153.110 ⚠
hypothetical protein
— OG7
TcCLB.510091.50 ⚠
chaperone protein DnaJ, putative
— OG7
TcCLB.506691.14 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.