TcCLB.510291.30

protein phosphatase 2C-like, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100270 OG7: OG7_0000783 308 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 308 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508131.19 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
TcCLB.503813.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.509453.4 ⚠
hypothetical protein, conserved
— Both
TcCLB.506357.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510771.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.510773.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.507047.80 ⚠
zinc-finger protein ZPR1, putative
— OG7
TcCLB.508277.140 ⚠
phosphomevalonate kinase protein, putative
— OG7
TcCLB.506925.100 ⚠
SCAMP family, putative
— OG7
TcCLB.506925.410 ⚠
ATPase, putative
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.504153.180 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
TcCLB.504103.30 ⚠
myosin heavy chain, putative
— OG7
TcCLB.506945.20 ⚠
PAS-domain containing phosphoglycerate kinase
— OG7
TcCLB.508569.80 ⚠
phosphoacetylglucosamine mutase, putative
— OG7
TcCLB.504867.20 ⚠
ABC transporter, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.508777.100 ⚠
cyclin 1
— OG7
TcCLB.509203.30 ⚠
hd phosphohydrolase family protein
— OG7
TcCLB.507739.110 ⚠
myosin IB heavy chain, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511419.50 ⚠
3-phosphoglycerate kinase, glycosomal
— OG7
TcCLB.503897.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508387.70 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
TcCLB.506945.359 ⚠
damage-specific DNA binding protein, putative
— OG7
TcCLB.509165.49 ⚠
damage-specific DNA binding protein, putative
— OG7
TcCLB.506811.190 ⚠
UDP-galactose 4-epimerase
— OG7
TcCLB.511127.110 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcCLB.504427.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504047.5 ⚠
urocanate hydratase, putative (fragment)
— OG7
TcCLB.506251.50 ⚠
Cell division control protein 48, putative
— OG7
TcCLB.511555.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510243.50 ⚠
UMP/CMP kinase, putative
— OG7
TcCLB.505987.50 ⚠
adenosine kinase, putative
— OG7
TcCLB.504147.80 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcCLB.503479.30 ⚠
adenylate kinase 1
— OG7
TcCLB.509965.370 ⚠
adenosine kinase, putative
— OG7
TcCLB.506357.140 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
TcCLB.506411.10 ⚠
metallo-peptidase, clan MA(E), family M3, put
— OG7
TcCLB.506947.90 ⚠
adenylate kinase, putative
— OG7
TcCLB.509965.380 ⚠
dTDP-glucose 4,6-dehydratase, putative
— OG7
TcCLB.508541.190 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.506239.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510609.110 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcCLB.511545.100 ⚠
RNA methyltransferase, putative
— OG7
TcCLB.511217.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504643.49 ⚠
hypothetical protein, conserved (fragment)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.