TcCLB.510101.150

adaptin-related protein-like, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_156708 OG7: OG7_0001921 200 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 200 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511585.40 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcCLB.507093.63 ⚠
RNA-binding protein, putative
— OG7
TcCLB.503689.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508347.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506661.110 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG7
TcCLB.506625.200 ⚠
exosome complex exonuclease, putative, riboso
— OG7
TcCLB.505807.270 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.507483.80 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG7
TcCLB.511545.100 ⚠
RNA methyltransferase, putative
— OG7
TcCLB.509151.80 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcCLB.508921.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.505123.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506357.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510841.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510879.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510311.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— OG7
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— OG7
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— OG7
TcCLB.507011.60 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG7
TcCLB.511421.110 ⚠
developmentally regulated phosphoprotein, put
— OG7
TcCLB.506183.9 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
TcCLB.507547.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503529.10 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.506179.59 ⚠
ATP-dependent RNA helicase, putative (fragmen
— OG7
TcCLB.511315.9 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.509625.10 ⚠
ATP-dependent RNA helicase, putative (fragmen
— OG7
TcCLB.506947.90 ⚠
adenylate kinase, putative
— OG7
TcCLB.506357.140 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
TcCLB.503479.30 ⚠
adenylate kinase 1
— OG7
TcCLB.510243.50 ⚠
UMP/CMP kinase, putative
— OG7
TcCLB.507811.20 ⚠
delta-adaptin, putative, adaptor complex prot
— OG7
TcCLB.506251.50 ⚠
Cell division control protein 48, putative
— OG7
TcCLB.503619.39 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506775.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506945.359 ⚠
damage-specific DNA binding protein, putative
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.508387.70 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
TcCLB.504427.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.414517.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.510515.100 ⚠
coronin, putative
— OG7
TcCLB.508209.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509165.49 ⚠
damage-specific DNA binding protein, putative
— OG7
TcCLB.506773.20 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.