TcCLB.506183.9

pyruvate dehydrogenase (lipoamide) kinase, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_146742 OG7: OG7_0002830 123 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 123 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— +1 more Both
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— +1 more Both
TcCLB.507537.30 ⚠
cysteinyl-tRNA synthetase, putative
— +1 more Both
TcCLB.506531.60 ⚠
hypothetical protein, conserved
— +1 more Both
TcCLB.511067.10 ⚠
tubulin folding cofactor D, putative
— +1 more Both
TcCLB.511421.110 ⚠
developmentally regulated phosphoprotein, put
— Both
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— +1 more Both
TcCLB.508183.4 ⚠
aspartyl aminopeptidase, putative (fragment)
— Both
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— +1 more Both
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.507011.80
zinc finger protein, putative
— OG6
TcCLB.506753.210 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506755.50 ⚠
PPPDE putative peptidase domain containing pr
— Both
TcCLB.511421.200
ARM-like helical domain-containing protein
— OG6
TcCLB.506237.19 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506755.90 ⚠
PPPDE putative peptidase domain containing pr
— Both
TcCLB.510181.90 ⚠
hypothetical protein, conserved
— Both
TcCLB.480997.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510741.10 ⚠
cystathione gamma lyase, putative
— Both
TcCLB.510739.19 ⚠
cystathione gamma lyase, putative (fragment)
— Both
TcCLB.506525.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.503885.90 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
TcCLB.509803.40 ⚠
5-oxoprolinase, putative
— Both
TcCLB.504153.140 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.503903.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508387.160 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.508181.20 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.506947.80 ⚠
arginine N-methyltransferase, type I
— OG7
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— +2 more OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506591.4 ⚠
heat shock protein 90, putative
— +2 more OG7
TcCLB.504153.310 ⚠
heat shock protein, putative
— +2 more OG7
TcCLB.506147.30 ⚠
synaptojanin (N-terminal domain), putative, i
— OG7
TcCLB.510737.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509145.19 ⚠
hypothetical protein, conserved
— OG7
TcCLB.450061.10 ⚠
Glycerophosphoryl diester phosphodiesterase f
— OG7
TcCLB.509153.60 ⚠
lipin, putative
— OG7
TcCLB.510311.140 ⚠
arginine N-methyltransferase, putative
— OG7
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.