TcCLB.511421.200

ARM-like helical domain-containing protein
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_158280 OG7: OG7_0103096 58 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 58 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510101.250
hypothetical protein, conserved
— Both
TcCLB.507963.79 ⚠
nucleosome assembly protein, putative
— Both
TcCLB.508787.10
hypothetical protein, conserved
— OG6
TcCLB.503897.100
hypothetical protein, conserved
— OG6
TcCLB.506183.9
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG6
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— OG6
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— OG6
TcCLB.504427.50
5'-AMP-activated protein kinase subunit beta,
— OG6
TcCLB.468941.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG6
TcCLB.510313.20 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506691.14 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG6
TcCLB.511181.80
threonyl-tRNA synthetase, putative
— Both
TcCLB.505983.20 ⚠
nucleosome assembly protein-like protein, put
— Both
TcCLB.508585.10
hypothetical protein, conserved
— Both
TcCLB.506135.70
hypothetical protein, conserved
— Both
TcCLB.506755.279
hypothetical protein, conserved
— OG6
TcCLB.510741.10 ⚠
cystathione gamma lyase, putative
— OG6
TcCLB.510739.19 ⚠
cystathione gamma lyase, putative (fragment)
— OG6
TcCLB.509145.10
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— OG6
TcCLB.506525.50
hypothetical protein, conserved
— OG6
TcCLB.510101.210
PUB domain containing protein, putative
— OG6
TcCLB.509805.130
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
TcCLB.510165.30
R3H domain containing protein, putative
— OG6
TcCLB.503653.20
hypothetical protein, conserved
— OG6
TcCLB.507809.110
WD domain, G-beta repeat, putative
— OG6
TcCLB.506237.19 ⚠
hypothetical protein, conserved
— OG6
TcCLB.480997.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.507077.40
p21-C-terminal region-binding protein, putati
— OG6
TcCLB.509803.40
5-oxoprolinase, putative
— OG6
TcCLB.507747.220
protein farnesyltransferase, putative
— OG6
TcCLB.510741.40
hypothetical protein, conserved
— OG6
TcCLB.510431.170
hypothetical protein, conserved
— OG6
TcCLB.507011.80
zinc finger protein, putative
— OG6
TcCLB.510181.90
hypothetical protein, conserved
— OG6
TcCLB.511111.10
translation initiation factor IF-2, putative
— OG6
TcCLB.508647.220
mitochondrial RNA binding protein 1, mitochon
— Both
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG6
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG6
TcCLB.508951.90 ⚠
CHAT domain containing protein, putative
— OG6
TcCLB.506493.9 ⚠
CHAT domain containing protein, putative
— OG6
TcCLB.506457.130
Domain of unknown function (DUF4042), putativ
— OG6
TcCLB.507537.30 ⚠
cysteinyl-tRNA synthetase, putative
— OG6
TcCLB.506531.60 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511751.70
microtubule associated protein xmap215
— OG6
TcCLB.510761.60
casein kinase II, putative
— OG6
TcCLB.511067.10
tubulin folding cofactor D, putative
— OG6
TcCLB.508675.60
hypothetical protein, conserved
— Both
TcCLB.508265.100
cytoskeleton associated protein, putative
— Both
TcCLB.509127.70
Nop14-like family, putative
— OG6
TcCLB.504125.70 ⚠
hypothetical protein, conserved
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.