TcCLB.506531.60

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100332 OG7: OG7_0003299 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509805.130 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— +2 more Both
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.511181.80 ⚠
threonyl-tRNA synthetase, putative
— Both
TcCLB.511067.10 ⚠
tubulin folding cofactor D, putative
— Both
TcCLB.506183.9 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.511421.110 ⚠
developmentally regulated phosphoprotein, put
— Both
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcCLB.507809.110 ⚠
WD domain, G-beta repeat, putative
— Both
TcCLB.510101.200 ⚠
zinc finger ccch and cchc domain-containing p
— Both
TcCLB.510877.60 ⚠
ruvB-like DNA helicase, putative
— Both
TcCLB.468941.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— Both
TcCLB.510313.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.506691.14 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— Both
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.508277.160 ⚠
glutaminyl-tRNA synthetase, putative
— Both
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— Both
TcCLB.506941.130 ⚠
SET domain containing protein, putative
— Both
TcCLB.510101.210 ⚠
PUB domain containing protein, putative
— Both
TcCLB.511585.40 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
TcCLB.503885.90 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
TcCLB.511693.10 ⚠
hypothetical protein
— Both
TcCLB.511555.60 ⚠
ubiquitin ligase, putative
— Both
TcCLB.511589.260 ⚠
glycyl-tRNA synthetase, putative
— Both
TcCLB.504017.79 ⚠
glycyl-tRNA synthetase, putative
— Both
TcCLB.508347.120 ⚠
hypothetical protein, conserved
— Both
TcCLB.503689.40 ⚠
hypothetical protein, conserved
— Both
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.511001.190 ⚠
vacuolar ATP synthase subunit d, putative
— Both
TcCLB.504153.140 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.507211.10 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.503685.30 ⚠
carnitine/choline acetyltransferase, putative
— OG7
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.508181.20 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.506127.170 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.507509.80 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.510349.30 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.