TcCLB.510877.60

ruvB-like DNA helicase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101635 OG7: OG7_0003574 41 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 41 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511145.70 ⚠
centromere/microtubule binding protein cbf5,
— +3 more Both
TcCLB.505989.82 ⚠
ruvB-like DNA helicase, putative
— Both
TcCLB.506363.90 ⚠
amidohydrolase, putative
— Both
TcCLB.506227.150 ⚠
protein kinase A regulatory subunit
— OG7
TcCLB.506363.70 ⚠
amidohydrolase, putative
— Both
TcCLB.506351.80 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
TcCLB.504507.5 ⚠
trypanothione reductase, putative (fragment)
— Both
TcCLB.511557.10 ⚠
oligopeptidase b
— Both
TcCLB.484299.10 ⚠
trypanothione reductase, putative
— Both
TcCLB.511303.160 ⚠
sodium/hydrogen exchanger, putative
— Both
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— Both
TcCLB.507211.10 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.503685.30 ⚠
carnitine/choline acetyltransferase, putative
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.506503.69 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcCLB.507883.100 ⚠
malate dehydrogenase, putative
— OG7
TcCLB.506211.250 ⚠
fibrillarin, putative
— OG7
TcCLB.510105.50 ⚠
fibrillarin, putative
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.510719.260 ⚠
ATP-dependent protease subunit HslV, putative
— Both
TcCLB.508383.10 ⚠
Present in the outer mitochondrial membrane p
— Both
TcCLB.511303.40 ⚠
carnitine O-acetyltransferase, putative
— Both
TcCLB.511579.9 ⚠
fatty acyl CoA syntetase 1, putative (fragmen
— Both
TcCLB.511581.10 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcCLB.506829.110 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcCLB.511581.20 ⚠
fatty acyl CoA syntetase 1 (fragment)
— Both
TcCLB.506829.100 ⚠
fatty acyl CoA syntetase 1, putative
— Both
TcCLB.503575.50 ⚠
fatty acyl CoA synthetase, putative
— Both
TcCLB.510611.79 ⚠
Present in the outer mitochondrial membrane p
— Both
TcCLB.509965.330 ⚠
hypothetical protein, conserved
— Both
TcCLB.507883.109 ⚠
mitochondrial malate dehydrogenase, putative
— Both
TcCLB.507537.30 ⚠
cysteinyl-tRNA synthetase, putative
— Both
TcCLB.506531.60 ⚠
hypothetical protein, conserved
— Both
TcCLB.506941.130 ⚠
SET domain containing protein, putative
— Both
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.506825.100 ⚠
hypothetical protein, conserved
— Both
TcCLB.511729.60 ⚠
MORN repeat-containing protein 1
— Both
TcCLB.510351.90 ⚠
dihydrolipoamide branched chain transacylase,
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.