TcCLB.511557.10

oligopeptidase b
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102873 OG7: OG7_0003174 49 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 49 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506503.69 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcCLB.503637.30 ⚠
serine peptidase, Clan SC, Family S9B
— Both
TcCLB.507883.109 ⚠
mitochondrial malate dehydrogenase, putative
— Both
TcCLB.505989.82 ⚠
ruvB-like DNA helicase, putative
— OG7
TcCLB.508771.20 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.509099.50 ⚠
trypanothione synthetase
— OG7
TcCLB.508771.10 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.486465.9 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.504427.10 ⚠
trypanothione synthetase, putative
— OG7
TcCLB.506467.29 ⚠
methyltransferase domain containing protein,
— OG7
TcCLB.504143.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.441401.10 ⚠
imidazolonepropienase, putative
— OG7
TcCLB.509137.30 ⚠
imidazolonepropionase, putative
— OG7
TcCLB.506857.110 ⚠
Uncharacterised protein family UPF0066, putat
— Both
TcCLB.507883.100 ⚠
malate dehydrogenase, putative
— OG7
TcCLB.506529.90 ⚠
metallo-peptidase, clan MA(E), family M1, put
— OG7
TcCLB.511051.70 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG7
TcCLB.503671.10 ⚠
Aminopeptidase M1, putative (fragment)
— OG7
TcCLB.510325.69 ⚠
Aminopeptidase M1, putative (fragment)
— OG7
TcCLB.506411.10 ⚠
metallo-peptidase, clan MA(E), family M3, put
— OG7
TcCLB.504147.80 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.511559.20 ⚠
Uncharacterised protein family (UPF0160), put
— OG7
TcCLB.503971.40 ⚠
translation initiation factor 2 subunit, puta
— OG7
TcCLB.506127.150 ⚠
BRO1-like domain/ALIX V-shaped domain binding
— OG7
TcCLB.510613.30 ⚠
hypothetical protein
— Both
TcCLB.509167.100 ⚠
valyl-tRNA synthetase, putative
— Both
TcCLB.510611.79 ⚠
Present in the outer mitochondrial membrane p
— Both
TcCLB.509965.330 ⚠
hypothetical protein, conserved
— Both
TcCLB.508383.10 ⚠
Present in the outer mitochondrial membrane p
— Both
TcCLB.507389.70 ⚠
peptidase, putative, metallo-peptidase, Clan
— Both
TcCLB.511049.40 ⚠
leucyl-tRNA synthetase, putative
— Both
TcCLB.510997.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.508539.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.506945.50 ⚠
T-complex protein 11, putative
— Both
TcCLB.504507.5 ⚠
trypanothione reductase, putative (fragment)
— Both
TcCLB.484299.10 ⚠
trypanothione reductase, putative
— Both
TcCLB.509351.10 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcCLB.510737.100 ⚠
Peroxin 19
— Both
TcCLB.510877.60 ⚠
ruvB-like DNA helicase, putative
— Both
TcCLB.506715.40 ⚠
hypothetical protein, conserved
— Both
TcCLB.511589.260 ⚠
glycyl-tRNA synthetase, putative
— Both
TcCLB.504119.29 ⚠
deoxyhypusine synthase, putative
— Both
TcCLB.504017.79 ⚠
glycyl-tRNA synthetase, putative
— Both
TcCLB.511421.60 ⚠
deoxyhypusine synthase, putative
— Both
TcCLB.506363.90 ⚠
amidohydrolase, putative
— Both
TcCLB.506363.70 ⚠
amidohydrolase, putative
— Both
TcCLB.511303.160 ⚠
sodium/hydrogen exchanger, putative
— Both
TcCLB.510243.80 ⚠
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.