TcCLB.506529.90

metallo-peptidase, clan MA(E), family M1, putative, puromycin-sensitive aminopeptidase-like protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_156775 OG7: OG7_0001210 35 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 35 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503841.70 ⚠
aspartate aminotransferase, putative
— OG7
TcCLB.511557.10 ⚠
oligopeptidase b
— OG7
TcCLB.511691.20 ⚠
cystathionine beta-synthase, cysteine synthas
— OG7
TcCLB.509149.9 ⚠
cystathionine beta-synthase, serine sulfhydry
— OG7
TcCLB.506529.420 ⚠
glutamic--pyruvic transaminase, putative, ala
— OG7
TcCLB.506529.430 ⚠
alanine aminotransferase, putative, glutamic-
— OG7
TcCLB.506351.80 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
TcCLB.504153.160 ⚠
Metallocarboxypeptidase 1
— OG7
TcCLB.506467.29 ⚠
methyltransferase domain containing protein,
— OG7
TcCLB.506553.20 ⚠
bromodomain factor 2 protein
— OG7
TcCLB.510381.10 ⚠
cystathionine beta-synthase, putative
— OG7
TcCLB.510719.70 ⚠
bromodomain-containing protein 3
— OG7
TcCLB.504213.80 ⚠
threonine synthase, putative
— OG7
TcCLB.504143.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506127.150 ⚠
BRO1-like domain/ALIX V-shaped domain binding
— OG7
TcCLB.511469.100 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— OG7
TcCLB.504507.5 ⚠
trypanothione reductase, putative (fragment)
— OG7
TcCLB.484299.10 ⚠
trypanothione reductase, putative
— OG7
TcCLB.508375.30 ⚠
aspartate carbamoyltransferase, putative
— OG7
TcCLB.508537.5 ⚠
tyrosine aminotransferase, putative (fragment
— OG7
TcCLB.508535.50 ⚠
tyrosine aminotransferase
— OG7
TcCLB.503747.10 ⚠
glutamine aminotransferase, putative (fragmen
— OG7
TcCLB.508993.10 ⚠
cytidine triphosphate synthase, putative
— OG7
TcCLB.511393.10 ⚠
sterol carrier protein, putative, nonspecific
— OG7
TcCLB.507091.50 ⚠
aspartate carbamoyltransferase, putative
— OG7
TcCLB.510737.10 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— OG7
TcCLB.503899.90 ⚠
asparagine synthetase a, putative
— OG7
TcCLB.511691.10 ⚠
cysteine synthase, cystathionine beta-synthas
— OG7
TcCLB.507011.269 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— OG7
TcCLB.510507.20 ⚠
3-ketoacyl-CoA thiolase, putative
— OG7
TcCLB.508387.20 ⚠
methylthioadenosine phosphorylase, putative
— OG7
TcCLB.509153.90 ⚠
dihydrofolate reductase-thymidylate synthase
— OG7
TcCLB.508241.149 ⚠
cystathionine beta-synthase, putative (fragme
— OG7
TcCLB.508241.140 ⚠
serine sulfhydrylase, cysteine synthase, cyst
— OG7
TcCLB.510565.11 ⚠
tyrosine aminotransferase, putative (fragment
— OG7
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.