TcCLB.506363.80

N-acyl-L-amino acid amidohydrolase, putative, aminoacylase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_157343 OG7: OG7_0005942 134 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 134 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504153.140 ⚠
metallo-peptidase, Clan MF, Family M17
— +4 more OG7
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— OG7
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— OG7
TcCLB.504137.10 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
TcCLB.506135.90 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.506503.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503579.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.508385.30 ⚠
CYC2-like cyclin, putative
— OG7
TcCLB.506857.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506127.20 ⚠
mRNA export factor MEX67
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511577.50 ⚠
endo-beta-N-acetylglucosaminidase, putative
— OG7
TcCLB.511555.80 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcCLB.509167.170 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
TcCLB.503551.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511369.10 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.507735.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508271.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.417091.10 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.510769.30 ⚠
U3 small nucleolar RNA-associated protein 6,
— OG7
TcCLB.510611.79 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.509965.330 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508383.10 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.508089.30 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
TcCLB.510407.90 ⚠
serine hydroxymethyltransferase, putative
— OG7
TcCLB.511311.80 ⚠
N-alpha-acetyltransferase 35, NatC auxiliary
— OG7
TcCLB.511303.160 ⚠
sodium/hydrogen exchanger, putative
— OG7
TcCLB.504507.5 ⚠
trypanothione reductase, putative (fragment)
— OG7
TcCLB.484299.10 ⚠
trypanothione reductase, putative
— OG7
TcCLB.511313.20 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
TcCLB.510999.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509247.50 ⚠
methionyl-tRNA synthetase, putative
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.506795.44 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
TcCLB.507993.390 ⚠
pyruvate kinase 2, putative
— OG7
TcCLB.510719.310 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506181.150 ⚠
hypothetical protein (fragment)
— OG7
TcCLB.511557.10 ⚠
oligopeptidase b
— OG7
TcCLB.506351.80 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
TcCLB.506825.130 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.