TcCLB.510999.10

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_152705 OG7: OG7_0043801 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.510321.20 ⚠
NOL1/NOP2/sun family, putative
— Both
TcCLB.506699.3 ⚠
NOL1/NOP2/sun family, putative
— Both
TcCLB.507929.20
co-chaperone GrpE, putative
— Both
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— Both
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— OG7
TcCLB.509805.40 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcCLB.511307.6 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcCLB.507713.40 ⚠
heat shock protein 85, putative (fragment)
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.506591.4 ⚠
heat shock protein 90, putative
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.507713.30 ⚠
heat shock protein 85, putative
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.504153.140
metallo-peptidase, Clan MF, Family M17
— Both
TcCLB.506933.20 ⚠
ribonucleoside-diphosphate reductase large ch
— Both
TcCLB.511217.200 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— Both
TcCLB.508321.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.510407.90
serine hydroxymethyltransferase, putative
— Both
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.504153.310 ⚠
heat shock protein, putative
— Both
TcCLB.510719.310
hypothetical protein, conserved
— Both
TcCLB.506363.90 ⚠
amidohydrolase, putative
— Both
TcCLB.506363.70 ⚠
amidohydrolase, putative
— Both
TcCLB.507047.80
zinc-finger protein ZPR1, putative
— Both
TcCLB.504073.30 ⚠
ribonucleoside-diphosphate reductase large ch
— Both
TcCLB.508089.30
N-terminal conserved domain of Nudc./CS domai
— Both
TcCLB.511311.80
N-alpha-acetyltransferase 35, NatC auxiliary
— Both
TcCLB.511181.90
peroxisome targeting signal 1 receptor, putat
— Both
TcCLB.509979.100
WD domain, G-beta repeat, putative
— Both
TcCLB.509247.50
methionyl-tRNA synthetase, putative
— Both
TcCLB.458015.10
VHS domain containing protein, putative
— Both
TcCLB.504137.10
isoleucyl-tRNA synthetase, putative
— Both
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— Both
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.