TcCLB.506933.20

ribonucleoside-diphosphate reductase large chain, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100448 OG7: OG7_0004229 96 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 96 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506801.120 ⚠
Calcium/calmodulin-dependent protein kinase k
— Both
TcCLB.511467.30 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcCLB.507677.140 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcCLB.510323.110 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcCLB.510747.10 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcCLB.511741.60 ⚠
leucyl/phenylalanyl-tRNA protein transferase,
— OG7
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— OG7
TcCLB.511427.10 ⚠
conserved protein, unknown function (fragment
— Both
TcCLB.511425.49 ⚠
conserved protein, unknown function (fragment
— Both
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— Both
TcCLB.510759.40 ⚠
protein kinase, putative
— Both
TcCLB.506505.40 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG6
TcCLB.503613.10 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcCLB.508987.39 ⚠
hypothetical protein, conserved
— Both
TcCLB.503971.40 ⚠
translation initiation factor 2 subunit, puta
— Both
TcCLB.503671.30 ⚠
leucine-rich repeat-containing protein
— Both
TcCLB.508307.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.503887.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.511729.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.511575.60 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TcCLB.508387.20 ⚠
methylthioadenosine phosphorylase, putative
— Both
TcCLB.510507.20 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
TcCLB.507091.50 ⚠
aspartate carbamoyltransferase, putative
— Both
TcCLB.507011.269 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
TcCLB.506591.4 ⚠
heat shock protein 90, putative
— OG7
TcCLB.511393.10 ⚠
sterol carrier protein, putative, nonspecific
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.511307.6 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506223.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.503677.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510769.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507713.30 ⚠
heat shock protein 85, putative
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.508375.30 ⚠
aspartate carbamoyltransferase, putative
— Both
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.509805.40 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.507713.40 ⚠
heat shock protein 85, putative (fragment)
— OG7
TcCLB.510143.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506945.220 ⚠
serine/arginine-rich protein specific kinase
— OG7
TcCLB.506775.190 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcCLB.510321.20 ⚠
NOL1/NOP2/sun family, putative
— Both
TcCLB.508089.30 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.