TcCLB.511425.49

conserved protein, unknown function (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_148265 OG7: OG7_0034456 6 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 6 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504073.30 ⚠
ribonucleoside-diphosphate reductase large ch
— Both
TcCLB.504073.10 ⚠
endonuclease/exonuclease/phosphatase, putativ
— Both
TcCLB.506933.20 ⚠
ribonucleoside-diphosphate reductase large ch
— Both
TcCLB.508215.3 ⚠
CMGC/SRPK protein kinase, putative
— Both
TcCLB.477079.10 ⚠
protein kinase, putative, CMGC/SRPK protein k
— Both
TcCLB.506945.220 ⚠
serine/arginine-rich protein specific kinase
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.