TcCLB.503671.30

leucine-rich repeat-containing protein
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_104522 OG7: OG7_0009175 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508949.4 ⚠
elongation factor 1-alpha (ef-1-alpha), putat
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.506775.190 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcCLB.503613.10 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcCLB.510231.20
hypothetical protein
— OG7
TcCLB.511741.60
leucyl/phenylalanyl-tRNA protein transferase,
— OG7
TcCLB.511369.10 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.511369.20 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.511369.30 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.511369.5 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcCLB.510759.40 ⚠
protein kinase, putative
— Both
TcCLB.506505.40 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG6
TcCLB.506801.120 ⚠
Calcium/calmodulin-dependent protein kinase k
— Both
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.511467.30 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcCLB.507677.140 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcCLB.510323.110 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcCLB.510747.10 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.511871.110
hypothetical protein, conserved
— OG6
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.509011.70
adrenodoxin precursor, putative
— Both
TcCLB.504883.50
tRNA synthetases class II (A)/Threonyl and Al
— Both
TcCLB.503971.40
translation initiation factor 2 subunit, puta
— Both
TcCLB.507735.10
hypothetical protein, conserved
— Both
TcCLB.508469.59
helicase, putative
— OG6
TcCLB.510743.70
lactoylglutathione lyase-like protein, putati
— Both
TcCLB.511041.4 ⚠
Sucrase/ferredoxin-like, putative
— Both
TcCLB.504137.80
adenylyl cyclase-associated protein, putative
— Both
TcCLB.504153.140
metallo-peptidase, Clan MF, Family M17
— Both
TcCLB.510101.140
pyruvate phosphate dikinase, putative
— Both
TcCLB.508307.70
hypothetical protein, conserved
— Both
TcCLB.503887.30
hypothetical protein, conserved
— Both
TcCLB.510719.310
hypothetical protein, conserved
— Both
TcCLB.510181.140
hypothetical protein, conserved
— Both
TcCLB.509157.250
Cation efflux family, putative
— Both
TcCLB.508993.20
homocysteine S-methyltransferase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.