TcCLB.508469.59

helicase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_146576 OG7: OG7_0000698 95 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 95 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
TcCLB.504213.20
Protein of unknown function (DUF1253), putati
— OG6
TcCLB.506691.14 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG6
TcCLB.506779.50
proteasome beta 3 subunit, putative
— OG6
TcCLB.507603.40
proteasome beta-1 subunit, putative
— OG6
TcCLB.416883.18
proteasome alpha 2 subunit, putative
— OG6
TcCLB.511531.40
chaperonin alpha subunit, putative
— OG6
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
TcCLB.506863.50 ⚠
ribosomal RNA processing protein 45, putative
— OG6
TcCLB.504181.50
T-complex protein 1, delta subunit, putative
— OG6
TcCLB.507089.80 ⚠
exosome-associated protein 2, putative
— OG6
TcCLB.506885.350
proteasome alpha 1 subunit, putative
— OG6
TcCLB.511313.20
Phosphorylated CTD interacting factor 1 WW do
— OG6
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— OG6
TcCLB.503613.20
proteasome alpha 7 subunit, putative
— OG6
TcCLB.430737.20 ⚠
hypothetical protein, conserved (fragment)
— OG6
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
TcCLB.504057.110
exosome complex exonuclease, putative, riboso
— OG6
TcCLB.504119.10
eukaryotic translation initiation factor 5, p
— OG6
TcCLB.510313.20 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
TcCLB.506795.90 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG6
TcCLB.506775.180
hypothetical protein, conserved
— OG6
TcCLB.468941.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG6
TcCLB.506203.70 ⚠
pre-mRNA-splicing factor ATP-dependent RNA he
— OG6
TcCLB.508241.120
rrp44p homologue, putative
— OG6
TcCLB.506739.50
ATP-dependent protease ATPase subunit HslU1,
— OG6
TcCLB.507797.9
nuclear transcription factor, putative
— OG6
TcCLB.506363.70 ⚠
amidohydrolase, putative
— OG6
TcCLB.506363.90 ⚠
amidohydrolase, putative
— OG6
TcCLB.510525.30
hypothetical protein, conserved
— OG6
TcCLB.506743.170 ⚠
Met-10+ like-protein, putative
— OG6
TcCLB.509537.10 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
TcCLB.511173.64 ⚠
Mucin-associated surface protein (MASP), subg
— OG6
TcCLB.510603.30 ⚠
hypothetical protein, conserved
— OG6
TcCLB.422041.9 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— OG6
TcCLB.511871.110
hypothetical protein, conserved
— OG6
TcCLB.508041.60
eukaryotic release factor 3, putative
— OG6
TcCLB.511555.80
ribonucleoside-diphosphate reductase small ch
— OG6
TcCLB.503653.20
hypothetical protein, conserved
— OG6
TcCLB.507735.10
hypothetical protein, conserved
— OG6
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— OG6
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— OG6
TcCLB.506239.60 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506181.150 ⚠
hypothetical protein (fragment)
— OG6
TcCLB.510777.10
hypothetical protein, conserved
— OG6
TcCLB.464807.20
PA26 p53-induced protein (sestrin), putative
— OG6
TcCLB.507927.40
hypothetical protein, conserved
— OG6
TcCLB.506227.230
N-alpha-acetyltransferase 10, NatA catalytic
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.