TcCLB.503653.20

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_146739 OG7: OG7_0042723 76 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 76 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511369.5 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcCLB.508465.60
hypothetical protein, conserved
— OG7
TcCLB.511369.30 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.510231.20
hypothetical protein
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.507797.9 ⚠
nuclear transcription factor, putative
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.511369.20 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.511585.50
hypothetical protein, conserved
— OG6
TcCLB.506691.14 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— Both
TcCLB.507735.10
hypothetical protein, conserved
— Both
TcCLB.508469.59
helicase, putative
— OG6
TcCLB.511127.110 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
TcCLB.509803.40
5-oxoprolinase, putative
— Both
TcCLB.503671.30
leucine-rich repeat-containing protein
— Both
TcCLB.508321.30
hypothetical protein, conserved
— OG6
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.511369.10 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.430539.10 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcCLB.510349.30
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.511351.9 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcCLB.508557.29 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.510105.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508949.4 ⚠
elongation factor 1-alpha (ef-1-alpha), putat
— OG7
TcCLB.506457.130
Domain of unknown function (DUF4042), putativ
— Both
TcCLB.510313.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.510719.310
hypothetical protein, conserved
— Both
TcCLB.510181.140
hypothetical protein, conserved
— Both
TcCLB.507747.220 ⚠
protein farnesyltransferase, putative
— Both
TcCLB.509127.70
Nop14-like family, putative
— Both
TcCLB.508041.60 ⚠
eukaryotic release factor 3, putative
— Both
TcCLB.468941.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— Both
TcCLB.504213.20
Protein of unknown function (DUF1253), putati
— Both
TcCLB.506519.130 ⚠
GMP reductase
— OG6
TcCLB.510741.40
hypothetical protein, conserved
— Both
TcCLB.508183.4
aspartyl aminopeptidase, putative (fragment)
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.