TcCLB.508183.4

aspartyl aminopeptidase, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102047 OG7: OG7_0006128 173 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 173 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506183.9 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— Both
TcCLB.511421.110 ⚠
developmentally regulated phosphoprotein, put
— OG7
TcCLB.509099.30
paraflagellar rod protein 5, putative
— OG7
TcCLB.510101.210
PUB domain containing protein, putative
— Both
TcCLB.509805.130
bifunctional aminoacyl-tRNA synthetase, putat
— Both
TcCLB.510165.30 ⚠
R3H domain containing protein, putative
— Both
TcCLB.510101.250
hypothetical protein, conserved
— Both
TcCLB.503653.20
hypothetical protein, conserved
— Both
TcCLB.508387.160 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— Both
TcCLB.509099.160 ⚠
hypothetical protein, conserved
— Both
TcCLB.506529.590 ⚠
Centrosomal protein of 164 kDa, putative
— Both
TcCLB.507809.110
WD domain, G-beta repeat, putative
— Both
TcCLB.509153.60
lipin, putative
— Both
TcCLB.506237.19 ⚠
hypothetical protein, conserved
— OG6
TcCLB.480997.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.509589.10 ⚠
mitochondrial DNA polymerase I protein D, put
— Both
TcCLB.508813.50
oxidoreductase-like protein, putative
— Both
TcCLB.507077.40
p21-C-terminal region-binding protein, putati
— Both
TcCLB.510293.54
Mitochondrial ATP synthase epsilon chain, put
— Both
TcCLB.509803.40
5-oxoprolinase, putative
— Both
TcCLB.506413.70
hypothetical protein, conserved
— Both
TcCLB.511369.5 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcCLB.511369.30 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.511369.20 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.508949.4 ⚠
elongation factor 1-alpha (ef-1-alpha), putat
— OG7
TcCLB.511369.10 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.503903.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504153.140
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510349.30
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506517.100 ⚠
ATPase family associated with various cellula
— OG7
TcCLB.511741.30 ⚠
replication factor C, subunit 2, putative
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.506227.80 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
TcCLB.507629.30 ⚠
Dpy-30 motif containing protein, putative
— OG7
TcCLB.507509.80 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcCLB.507527.20 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.504075.10 ⚠
kinetoplast poly(A) polymerase 1
— OG7
TcCLB.506657.70 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.