TcCLB.507509.80

PPPDE putative peptidase domain containing protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_146568 OG7: OG7_0003062 40 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 40 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510349.30 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcCLB.506493.9 ⚠
CHAT domain containing protein, putative
— OG7
TcCLB.508951.90 ⚠
CHAT domain containing protein, putative
— OG7
TcCLB.503897.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506183.9 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
TcCLB.511421.110 ⚠
developmentally regulated phosphoprotein, put
— OG7
TcCLB.510861.14 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.510859.50 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.508183.4 ⚠
aspartyl aminopeptidase, putative (fragment)
— OG7
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.506525.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506531.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507537.30 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
TcCLB.507547.30 ⚠
Mitochondrial-processing peptidase subunit al
— OG7
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.506735.10 ⚠
metallo-peptidase, Clan ME, Family M16, putat
— OG7
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.510257.130 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.510861.140 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.464807.10 ⚠
serine/threonine protein kinase, putative, CA
— OG7
TcCLB.511801.14 ⚠
protein lipid droplet kinase (LDK)
— OG7
TcCLB.511001.60 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.506493.50 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcCLB.510741.10 ⚠
cystathione gamma lyase, putative
— OG7
TcCLB.510739.19 ⚠
cystathione gamma lyase, putative (fragment)
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.510525.10 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508787.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509803.40 ⚠
5-oxoprolinase, putative
— OG7
TcCLB.510431.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507077.40 ⚠
p21-C-terminal region-binding protein, putati
— OG7
TcCLB.511067.10 ⚠
tubulin folding cofactor D, putative
— OG7
TcCLB.510181.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.