TcCLB.510181.90

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_147018 OG7: OG7_0042983 81 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 81 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509803.40
5-oxoprolinase, putative
— Both
TcCLB.506777.50 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcCLB.506223.40 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.510349.30
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcCLB.506513.150 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.509965.40 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.504125.30 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.506829.50
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TcCLB.482369.10
protein phosphatase 2A regulatory subunit, pu
— Both
TcCLB.507611.270 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506747.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— Both
TcCLB.507077.40
p21-C-terminal region-binding protein, putati
— Both
TcCLB.480997.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506237.19 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506945.70 ⚠
protein mkt1, putative
— Both
TcCLB.507011.250
Putative death-receptor fusion protein (DUF24
— Both
TcCLB.510431.170
hypothetical protein, conserved
— Both
TcCLB.511211.110
hypothetical protein, conserved
— Both
TcCLB.506861.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG6
TcCLB.511421.110 ⚠
developmentally regulated phosphoprotein, put
— OG7
TcCLB.504133.45 ⚠
Temperature dependent protein affecting M2 ds
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.507521.10
hypothetical protein, conserved
— OG7
TcCLB.503455.30
Protein of unknown function (DUF3648), putati
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510859.50 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.510861.14 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.508323.199 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG6
TcCLB.506755.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506755.200 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.507509.80 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcCLB.508727.44
hypothetical protein, conserved
— OG7
TcCLB.503905.50 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.508541.190 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcCLB.504103.90 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.506239.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511067.10
tubulin folding cofactor D, putative
— Both
TcCLB.511737.20
hypothetical protein, conserved
— Both
TcCLB.506941.260
hypothetical protein, conserved
— Both
TcCLB.507483.60
translation-associated element 2, putative
— Both
TcCLB.506755.90 ⚠
PPPDE putative peptidase domain containing pr
— Both
TcCLB.506755.50 ⚠
PPPDE putative peptidase domain containing pr
— Both
TcCLB.504125.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.