TcCLB.508323.199

ATP-dependent DEAD/H RNA helicase, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_126543 OG7: OG7_0000698 61 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 61 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509455.90 ⚠
Putative intraflagellar transport protein A1
— OG6
TcCLB.510737.70 ⚠
60S ribosomal subunit protein L31, putative
— OG6
TcCLB.503525.20 ⚠
Cyclin 12, L-type
— OG6
TcCLB.506223.110 ⚠
Microtubule-binding protein MIP-T3, putative
— OG6
TcCLB.507011.250 ⚠
Putative death-receptor fusion protein (DUF24
— OG6
TcCLB.508347.159 ⚠
microtubule-associated protein, putative, (fr
— OG6
TcCLB.508145.49 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511737.20 ⚠
hypothetical protein, conserved
— OG6
TcCLB.504171.50 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506945.70 ⚠
protein mkt1, putative
— OG6
TcCLB.504153.150 ⚠
Unc104-like kinesin, putative
— OG6
TcCLB.503975.70 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510181.90 ⚠
hypothetical protein, conserved
— OG6
TcCLB.504043.10 ⚠
General negative regulator of transcription s
— OG6
TcCLB.506697.30 ⚠
Serine/threonine-protein kinase NEK6, putativ
— OG6
TcCLB.511211.110 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510761.60 ⚠
casein kinase II, putative
— OG6
TcCLB.506215.19 ⚠
intraflagellar transport protein 140, putativ
— OG6
TcCLB.505807.40 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510515.80 ⚠
hypothetical protein, conserved
— OG6
TcCLB.503959.30 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511365.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511621.150 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511365.4 ⚠
hypothetical protein, conserved (fragment)
— OG6
TcCLB.511363.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506857.90 ⚠
proteasome regulatory ATPase subunit 1, putat
— OG6
TcCLB.506747.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG6
TcCLB.482369.10 ⚠
protein phosphatase 2A regulatory subunit, pu
— OG6
TcCLB.507603.20 ⚠
translation initiation factor EIF-2b alpha su
— OG6
TcCLB.506829.50 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
TcCLB.506755.160 ⚠
AAA ATPase, putative
— OG6
TcCLB.506769.120 ⚠
Mucin-associated surface protein (MASP), subg
— OG6
TcCLB.505977.13 ⚠
serine/threonine-protein kinase, putative (fr
— OG6
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG6
TcCLB.506227.240 ⚠
hypothetical protein, conserved
— OG6
TcCLB.507603.110 ⚠
hypothetical protein, conserved
— OG6
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— OG6
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— OG6
TcCLB.508387.90 ⚠
paraflagellar rod protein, putative
— OG6
TcCLB.506211.250 ⚠
fibrillarin, putative
— OG6
TcCLB.510105.50 ⚠
fibrillarin, putative
— OG6
TcCLB.507483.60 ⚠
translation-associated element 2, putative
— OG6
TcCLB.510025.170 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.507817.80 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG6
TcCLB.506351.9 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG6
TcCLB.507641.80 ⚠
5'-3' exoribonuclease D, putative
— OG6
TcCLB.508989.90 ⚠
Eukaryotic translation initiation factor 4 ga
— OG6
TcCLB.511605.30 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.504033.180 ⚠
hypothetical protein, conserved
— OG6
TcCLB.508989.70 ⚠
hypothetical protein, conserved
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.