TcCLB.505977.13

serine/threonine-protein kinase, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_156902 OG7: OG7_0000432 95 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 95 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506769.120 ⚠
Mucin-associated surface protein (MASP), subg
— OG6
TcCLB.511605.30 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.506215.19
intraflagellar transport protein 140, putativ
— OG6
TcCLB.504255.30
hypothetical protein, conserved
— OG6
TcCLB.508989.70
hypothetical protein, conserved
— OG6
TcCLB.504033.180
hypothetical protein, conserved
— OG6
TcCLB.506945.320
hypothetical protein, conserved
— OG6
TcCLB.511585.30
hypothetical protein, conserved
— OG6
TcCLB.507641.80 ⚠
5'-3' exoribonuclease D, putative
— OG6
TcCLB.506351.9 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG6
TcCLB.507817.80 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG6
TcCLB.510025.170 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.511621.180 ⚠
Phosducin, putative
— OG6
TcCLB.509069.20 ⚠
ATP binding protein-like protein, putative
— OG6
TcCLB.509831.50
intraflagellar transport protein 88, putative
— OG6
TcCLB.509151.40
inorganic polyphosphate/ATP-NAD kinase, putat
— OG6
TcCLB.508387.90
paraflagellar rod protein, putative
— OG6
TcCLB.508647.210
dynein arm light chain, putative
— OG6
TcCLB.510491.10
Anaphase-promoting complex, cyclosome, subuni
— OG6
TcCLB.506227.240
hypothetical protein, conserved
— OG6
TcCLB.507603.110
hypothetical protein, conserved
— OG6
TcCLB.416883.18
proteasome alpha 2 subunit, putative
— OG6
TcCLB.509497.20
hypothetical protein, conserved
— OG6
TcCLB.504181.50
T-complex protein 1, delta subunit, putative
— OG6
TcCLB.506657.70
RNA editing 3' terminal uridylyl transferase
— OG6
TcCLB.508357.90
T-complex protein 1, beta subunit, putative
— OG6
TcCLB.506755.160
AAA ATPase, putative
— OG6
TcCLB.511531.40
chaperonin alpha subunit, putative
— OG6
TcCLB.507603.20
translation initiation factor EIF-2b alpha su
— OG6
TcCLB.503821.19
hypothetical protein, conserved
— OG6
TcCLB.506211.40
intraflagellar transport protein 52
— OG6
TcCLB.506885.350
proteasome alpha 1 subunit, putative
— OG6
TcCLB.503613.20
proteasome alpha 7 subunit, putative
— OG6
TcCLB.506795.20
hypothetical protein, conserved
— OG6
TcCLB.510091.90
hypothetical protein, conserved
— OG6
TcCLB.506529.460
TPR repeat, putative
— OG6
TcCLB.506659.10
tc40 antigen-like, putative, immunodominant a
— OG6
TcCLB.509267.50
U5 small nuclear ribonucleoprotein component,
— OG6
TcCLB.511867.50
proteasome alpha 7 subunit, putative
— OG6
TcCLB.509583.10
chaperonin TCP20, putative
— OG6
TcCLB.506743.150
proteasome 26S non-ATPase subunit 9, putative
— OG6
TcCLB.510515.139 ⚠
T-complex protein 1, gamma subunit, putative
— OG6
TcCLB.510517.10 ⚠
chaperonin/T-complex protein 1 gamma subunit,
— OG6
TcCLB.506221.50
coatomer subunit epsilon
— OG6
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG6
TcCLB.510351.80
Pre-mRNA polyadenylation factor FIP1
— OG6
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG6
TcCLB.510531.30
Galactose oxidase, central domain containing
— OG6
TcCLB.510763.40
proteasome complex subunit Rpn13 ubiquitin re
— OG6
TcCLB.506223.110
Microtubule-binding protein MIP-T3, putative
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.