TcCLB.506697.30

Serine/threonine-protein kinase NEK6, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_147247 OG7: OG7_0001157 26 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 26 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— OG6
TcCLB.506829.50
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
TcCLB.482369.10
protein phosphatase 2A regulatory subunit, pu
— OG6
TcCLB.506747.30
ubiquitin hydrolase, putative, cysteine pepti
— OG6
TcCLB.511211.110
hypothetical protein, conserved
— OG6
TcCLB.504047.40
kinesin, putative
— OG6
TcCLB.506861.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG6
TcCLB.508323.199 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG6
TcCLB.503953.50
Beta-lactamase superfamily domain containing
— OG6
TcCLB.508277.360
ubiquitin hydrolase, putative, cysteine pepti
— OG6
TcCLB.509967.40
Aminoacyl-tRNA editing domain containing prot
— OG6
TcCLB.506625.80
cAMP-specific phosphodiesterase, putative
— OG6
TcCLB.507483.60
translation-associated element 2, putative
— OG6
TcCLB.510761.60
casein kinase II, putative
— OG6
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— OG6
TcCLB.508989.90
Eukaryotic translation initiation factor 4 ga
— OG6
TcCLB.503959.30
hypothetical protein, conserved
— OG6
TcCLB.510181.90
hypothetical protein, conserved
— OG6
TcCLB.503975.70
hypothetical protein, conserved
— OG6
TcCLB.504153.150
Unc104-like kinesin, putative
— OG6
TcCLB.506945.70
protein mkt1, putative
— OG6
TcCLB.504171.50
hypothetical protein, conserved
— OG6
TcCLB.511737.20
hypothetical protein, conserved
— OG6
TcCLB.507011.250
Putative death-receptor fusion protein (DUF24
— OG6
TcCLB.503525.20
Cyclin 12, L-type
— OG6
TcCLB.506941.260
hypothetical protein, conserved
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.