TcCLB.508989.90

Eukaryotic translation initiation factor 4 gamma 5
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_139892 OG7: OG7_0037732 92 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 92 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507511.40
G5-interacting protein, putative
— Both
TcCLB.509129.10 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcCLB.507979.4 ⚠
histone H2A variant Z (fragment)
— OG7
TcCLB.509007.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510073.70
CCR4-NOT transcription complex subunit 2, put
— Both
TcCLB.509247.30
CCR4-NOT transcription complex subunit 1
— Both
TcCLB.506773.120
mRNA cap guanine-N7 methyltransferase, putati
— Both
TcCLB.506829.50
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TcCLB.508207.180
Eukaryotic translation initiation factor 4E t
— Both
TcCLB.506925.300 ⚠
cyclophilin a, putative
— OG6
TcCLB.510259.50 ⚠
21 kDa cyclophilin, putative, PPIase, putativ
— OG6
TcCLB.509499.10 ⚠
cyclophilin, putative, peptidyl-prolyl cis-tr
— OG6
TcCLB.503953.50
Beta-lactamase superfamily domain containing
— Both
TcCLB.506755.200 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511687.10 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcCLB.511687.19 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcCLB.509141.40 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcCLB.504225.20 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcCLB.506933.60 ⚠
mitochondrial RNA binding protein, putative
— Both
TcCLB.510525.90 ⚠
histone H2A, putative
— Both
TcCLB.510525.110 ⚠
histone H2A, putative
— Both
TcCLB.508321.11 ⚠
histone H2A, putative (fragment)
— Both
TcCLB.508321.21 ⚠
histone H2A, putative
— Both
TcCLB.510525.100 ⚠
histone H2A, putative
— Both
TcCLB.507611.270 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507521.10
hypothetical protein, conserved
— OG7
TcCLB.506503.150 ⚠
histone H3 variant V
— OG7
TcCLB.503455.30
Protein of unknown function (DUF3648), putati
— OG7
TcCLB.509965.40 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.503905.50 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.508541.190 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.504103.90 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.506239.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510055.70
Kinetochore interacting protein 5, putative
— OG7
TcCLB.506465.30
hypothetical protein, conserved
— OG7
TcCLB.506513.200 ⚠
histone H2A variant Z (fragment)
— OG7
TcCLB.504125.30 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.503975.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508727.44
hypothetical protein, conserved
— OG7
TcCLB.506777.50 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcCLB.504133.45 ⚠
Temperature dependent protein affecting M2 ds
— OG7
TcCLB.506223.40 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.506513.150 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.506885.413 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— OG7
TcCLB.506755.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510525.80 ⚠
histone H2A, putative
— Both
TcCLB.510105.50 ⚠
fibrillarin, putative
— Both
TcCLB.506945.70 ⚠
protein mkt1, putative
— Both
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.