TcCLB.464807.10

serine/threonine protein kinase, putative, CAMK/CAMKL family protein kinase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_105113 OG7: OG7_0000009 174 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 174 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506885.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511585.190 ⚠
Eukaryotic initiation factor 4A-1
— OG7
TcCLB.510323.20 ⚠
Flagellum attachment zone protein 19, putativ
— Both
TcCLB.511801.50 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
TcCLB.511577.40 ⚠
35 kDa cyclophilin, putative, rotamase, putat
— OG6
TcCLB.503893.60 ⚠
UBA/TS-N domain containing protein, putative
— Both
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.506755.50 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcCLB.506755.90 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcCLB.507509.80 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcCLB.504125.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507047.60 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
TcCLB.505843.30 ⚠
DNA repair protein Rad9, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.511421.60 ⚠
deoxyhypusine synthase, putative
— OG7
TcCLB.511303.80 ⚠
Organic solute transport protein 1, putative
— OG7
TcCLB.506107.20 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.511427.19 ⚠
conserved protein, unknown function (fragment
— OG7
TcCLB.510053.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504119.29 ⚠
deoxyhypusine synthase, putative
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511573.20 ⚠
hypothetical protein
— OG7
TcCLB.504883.50 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— OG7
TcCLB.511733.110 ⚠
GTPase activating protein of Rab-like GTPase,
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.509801.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.510101.250 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506863.10 ⚠
alanyl-tRNA synthetase, putative
— OG7
TcCLB.503579.60 ⚠
hypothetical protein
— OG7
TcCLB.507993.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511199.9 ⚠
ATP-dependent RNA helicase FAL1, putative (fr
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.510777.29 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.504935.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.