TcCLB.506107.20

dihydrouridine synthase (Dus), putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101867 OG7: OG7_0002064 202 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 202 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506945.80 ⚠
DNA ligase I, putative
— Both
TcCLB.507047.60 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
TcCLB.511741.50 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
TcCLB.506289.60 ⚠
Cupin-like domain containing protein, putativ
— OG7
TcCLB.509551.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.503487.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.503637.30 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
TcCLB.510283.70 ⚠
glycosyl hydrolase-like protein, putative
— OG7
TcCLB.510599.30 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
TcCLB.507993.260 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506927.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— OG7
TcCLB.506925.260 ⚠
Atypical serine/threonine protein kinase BUD3
— OG7
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TcCLB.511733.110 ⚠
GTPase activating protein of Rab-like GTPase,
— OG7
TcCLB.506363.130 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG7
TcCLB.506513.50 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.506775.30 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.506743.210 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.506941.80 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.510141.20 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcCLB.506885.270 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.509011.40 ⚠
calreticulin, putative
— OG7
TcCLB.509801.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506505.40 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcCLB.506467.40 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.504421.10 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.503599.10 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.506467.50 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.508723.100 ⚠
rab-like GTPase activating protein, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.110 ⚠
importin alpha, putative
— OG7
TcCLB.504137.10 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
TcCLB.506743.220 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509103.4 ⚠
protein kinase, putative
— OG7
TcCLB.506745.4 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.399033.19 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.