TcCLB.506467.50

serine/threonine protein kinase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_388901 OG7: OG7_0000003 92 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 92 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.503487.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510599.30 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— OG7
TcCLB.506945.80 ⚠
DNA ligase I, putative
— OG7
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503885.90 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
TcCLB.509965.110 ⚠
importin alpha, putative
— OG7
TcCLB.504137.10 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
TcCLB.508723.100 ⚠
rab-like GTPase activating protein, putative
— OG7
TcCLB.508723.80 ⚠
disgorgin, putative
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.506363.130 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG7
TcCLB.509247.50 ⚠
methionyl-tRNA synthetase, putative
— OG7
TcCLB.506147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506405.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511049.40 ⚠
leucyl-tRNA synthetase, putative
— OG7
TcCLB.504043.10 ⚠
General negative regulator of transcription s
— OG7
TcCLB.510533.120 ⚠
translation initiation factor IF-2, putative
— OG7
TcCLB.504035.90 ⚠
translation initiation factor IF-2, putative
— OG7
TcCLB.509669.90 ⚠
XPC-binding domain/UBA/TS-N domain containing
— OG7
TcCLB.509167.100 ⚠
valyl-tRNA synthetase, putative
— OG7
TcCLB.508387.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510617.19 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510997.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511439.100 ⚠
p-nitrophenylphosphatase, putative
— OG7
TcCLB.508955.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507227.9 ⚠
TPR repeat/SET domain containing protein, put
— OG7
TcCLB.511307.6 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.506699.3 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.509805.40 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcCLB.510321.20 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.509123.30 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
TcCLB.508463.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.399033.19 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
TcCLB.511741.50 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.504431.109 ⚠
cytochrome b5, putative
— OG7
TcCLB.507993.260 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511421.60 ⚠
deoxyhypusine synthase, putative
— OG7
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.