TcCLB.511627.100

TPR-repeat protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_103410 OG7: OG7_0001150 367 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 367 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504867.20 ⚠
ABC transporter, putative
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— Both
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— Both
TcCLB.507929.20 ⚠
co-chaperone GrpE, putative
— OG7
TcCLB.506885.430 ⚠
lipoic acid containing carrier protein, putat
— OG7
TcCLB.504147.200 ⚠
19S proteasome regulatory subunit, Regulatory
— OG7
TcCLB.509007.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507993.280 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG7
TcCLB.508539.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509805.40 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.506677.10 ⚠
ubiquitin-like protein, putative
— OG7
TcCLB.510283.70 ⚠
glycosyl hydrolase-like protein, putative
— OG7
TcCLB.503467.9 ⚠
NADH-dependent fumarate reductase, putative (
— OG7
TcCLB.506859.20 ⚠
proteasome regulatory ATPase subunit 5, putat
— OG7
TcCLB.510311.70 ⚠
26S protease regulatory subunit, putative, se
— OG7
TcCLB.507739.70 ⚠
Carnosine N-methyltransferase, putative
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.506107.20 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.507257.70 ⚠
protein farnesyltransferase alpha subunit, pu
— OG7
TcCLB.508185.19 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.508463.29 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
TcCLB.509761.10 ⚠
Metallopeptidase family M24/FACT complex subu
— OG7
TcCLB.510215.10 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcCLB.506733.60 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
TcCLB.507507.20 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
TcCLB.504421.10 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.506467.40 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.510431.140 ⚠
dual specificity tyrosine-phosphorylation-reg
— OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510143.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506505.40 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcCLB.507603.200 ⚠
proteasome regulatory ATPase subunit 3, putat
— OG7
TcCLB.510431.110 ⚠
hypothetical protein
— OG7
TcCLB.508385.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506859.70 ⚠
guide RNA associated protein, GAP2, putative
— OG7
TcCLB.506753.130 ⚠
rhodanese-like domain containing protein, put
— OG7
TcCLB.506753.140 ⚠
rhodanese-like domain containing protein, put
— OG7
TcCLB.503467.20 ⚠
rhodanese-like domain containing protein, put
— OG7
TcCLB.506753.150 ⚠
rhodanese-like domain containing protein, put
— OG7
TcCLB.511127.110 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcCLB.508389.20 ⚠
hypothetical protein
— OG7
TcCLB.511215.119 ⚠
Paraflagellar rod protein 2
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.