TcCLB.506505.40

Calcium/calmodulin-dependent protein kinase kinase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100881 OG7: OG7_0000003 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506179.20 ⚠
hypothetical protein, conserved
— OG6
TcCLB.508987.39 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511729.50 ⚠
hypothetical protein, conserved
— OG6
TcCLB.504073.30 ⚠
ribonucleoside-diphosphate reductase large ch
— OG6
TcCLB.503887.30 ⚠
hypothetical protein, conserved
— OG6
TcCLB.508307.70 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506933.20 ⚠
ribonucleoside-diphosphate reductase large ch
— OG6
TcCLB.503671.30 ⚠
leucine-rich repeat-containing protein
— OG6
TcCLB.503971.40 ⚠
translation initiation factor 2 subunit, puta
— OG6
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— OG7
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— OG7
TcCLB.506863.10 ⚠
alanyl-tRNA synthetase, putative
— OG7
TcCLB.511731.10 ⚠
UV excision repair RAD23-like protein, putati
— OG7
TcCLB.429257.10 ⚠
Gar1/Naf1 RNA binding region, putative
— OG7
TcCLB.506941.130 ⚠
SET domain containing protein, putative
— OG7
TcCLB.510999.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506287.30 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcCLB.506773.44 ⚠
cytochrome b5, putative
— OG7
TcCLB.507047.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506753.110 ⚠
cytochrome b5-like protein, putative
— OG7
TcCLB.504431.109 ⚠
cytochrome b5, putative
— OG7
TcCLB.503653.60 ⚠
cytochrome b-domain protein, putative
— OG7
TcCLB.508215.9 ⚠
protein kinase C substrate protein, heavy cha
— OG7
TcCLB.509153.120 ⚠
acyl-CoA dehydrogenase, putative
— OG7
TcCLB.506743.80 ⚠
SMP-30/Gluconolaconase/LRE-like region, putat
— OG7
TcCLB.506773.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510603.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509011.40 ⚠
calreticulin, putative
— OG7
TcCLB.504867.20 ⚠
ABC transporter, putative
— OG7
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— OG7
TcCLB.511421.60 ⚠
deoxyhypusine synthase, putative
— OG7
TcCLB.507993.260 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506925.260 ⚠
Atypical serine/threonine protein kinase BUD3
— OG7
TcCLB.453917.9 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506107.20 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.510283.70 ⚠
glycosyl hydrolase-like protein, putative
— OG7
TcCLB.511217.200 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— OG7
TcCLB.508321.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508089.30 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
TcCLB.510053.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— OG7
TcCLB.503589.10 ⚠
GDP-mannose pyrophosphorylase
— OG7
TcCLB.509551.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503637.30 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
TcCLB.510407.90 ⚠
serine hydroxymethyltransferase, putative
— OG7
TcCLB.504119.29 ⚠
deoxyhypusine synthase, putative
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.507907.50 ⚠
hypothetical protein, conserved
— OG7
Page 1 of 3
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.