TcCLB.506925.260

Atypical serine/threonine protein kinase BUD32, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101388 OG7: OG7_0005083 145 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 145 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509551.140
hypothetical protein, conserved
— Both
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— OG7
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— Both
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— Both
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— +1 more Both
TcCLB.509167.170
tRNA (Guanine-1)-methyltransferase, putative
— OG7
TcCLB.506127.20 ⚠
mRNA export factor MEX67
— OG7
TcCLB.508271.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504867.20
ABC transporter, putative
— OG7
TcCLB.504883.50
tRNA synthetases class II (A)/Threonyl and Al
— OG7
TcCLB.510101.140
pyruvate phosphate dikinase, putative
— OG7
TcCLB.504153.300 ⚠
GTPase protein, putative
— OG7
TcCLB.506287.150 ⚠
GTP-binding protein, putative
— OG7
TcCLB.510351.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510609.30 ⚠
GTPase, putative
— OG7
TcCLB.504867.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510603.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506743.170 ⚠
Met-10+ like-protein, putative
— OG7
TcCLB.506505.40 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcCLB.506467.40 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.504421.10 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.506467.50 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.506513.50 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.509103.4 ⚠
protein kinase, putative
— OG7
TcCLB.508723.100 ⚠
rab-like GTPase activating protein, putative
— OG7
TcCLB.510777.10
hypothetical protein, conserved
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511751.210
phosphopantothenoylcysteine decarboxylase, pu
— OG7
TcCLB.511585.40
DNA-damage inducible protein DDI1-like protei
— OG7
TcCLB.506107.20 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.511217.200 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— OG7
TcCLB.508321.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.506363.90 ⚠
amidohydrolase, putative
— OG7
TcCLB.511307.6 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.503885.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506945.270 ⚠
cyclin, putative
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.508385.30 ⚠
CYC2-like cyclin, putative
— OG7
TcCLB.503551.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509805.40 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcCLB.506227.230
N-alpha-acetyltransferase 10, NatA catalytic
— OG7
TcCLB.511313.20
Phosphorylated CTD interacting factor 1 WW do
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.