TcCLB.511585.40

DNA-damage inducible protein DDI1-like protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101685 OG7: OG7_0006273 181 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 181 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504153.140
metallo-peptidase, Clan MF, Family M17
— +1 more Both
TcCLB.506287.150 ⚠
GTP-binding protein, putative
— OG7
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcCLB.503855.40 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TcCLB.506625.60 ⚠
inositol 5-phosphatase 1, putative
— Both
TcCLB.509805.210
hypothetical protein, conserved
— Both
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcCLB.508717.40
branch point binding protein, putative
— Both
TcCLB.511545.140 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511001.190
vacuolar ATP synthase subunit d, putative
— Both
TcCLB.511589.10
ATP synthase, putative
— Both
TcCLB.506563.220 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TcCLB.511571.40
hypothetical protein, conserved
— Both
TcCLB.511555.60
ubiquitin ligase, putative
— Both
TcCLB.508535.10 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
TcCLB.503885.90
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
TcCLB.511693.10
hypothetical protein
— Both
TcCLB.506857.110
Uncharacterised protein family UPF0066, putat
— Both
TcCLB.509007.20
hypothetical protein, conserved
— Both
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— Both
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcCLB.506733.60
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
TcCLB.511067.10
tubulin folding cofactor D, putative
— Both
TcCLB.507925.69
hypothetical protein, conserved
— Both
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.506859.70
guide RNA associated protein, GAP2, putative
— Both
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.506925.10 ⚠
hypothetical protein
— OG7
TcCLB.504153.300 ⚠
GTPase protein, putative
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.506925.260
Atypical serine/threonine protein kinase BUD3
— OG7
TcCLB.511041.50
flagellum transition zone component, putative
— OG7
TcCLB.506211.150
polyprenyl synthase, putative
— OG7
TcCLB.510877.55 ⚠
acyl-CoA binding protein, putative
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506265.160
hypothetical protein, conserved
— OG7
TcCLB.508271.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506953.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506625.249 ⚠
RNA pseudouridylate synthase protein, putativ
— OG7
TcCLB.506945.270 ⚠
cyclin, putative
— OG7
TcCLB.506739.190 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcCLB.504203.50 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— OG7
TcCLB.480785.10 ⚠
serine/threonine kinase, putative, CMGC/DYRK
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.