TcCLB.480785.10

serine/threonine kinase, putative, CMGC/DYRK protein kinase, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_150779 OG7: OG7_0001715 66 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 66 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511585.40 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcCLB.509761.10 ⚠
Metallopeptidase family M24/FACT complex subu
— OG7
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— OG7
TcCLB.509805.210 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508535.10 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcCLB.510213.110 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcCLB.503841.80 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcCLB.503467.9 ⚠
NADH-dependent fumarate reductase, putative (
— OG7
TcCLB.510215.10 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcCLB.511421.150 ⚠
leucine-rich repeat-containing protein
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504203.60 ⚠
TPR-repeat-containing chaperone protein DNAJ,
— OG7
TcCLB.510297.30 ⚠
TPR-repeat-containing chaperone protein DNAJ,
— OG7
TcCLB.510407.80 ⚠
chaperone protein DnaJ, putative
— OG7
TcCLB.510291.7 ⚠
TPR-repeat-containing chaperone protein DNAJ,
— OG7
TcCLB.510143.24 ⚠
Hsc70-interacting protein (Hip), putative
— OG7
TcCLB.508781.20 ⚠
ATP synthase, putative
— OG7
TcCLB.506755.200 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506755.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509805.130 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
TcCLB.506025.50 ⚠
Vacuolar proton pump subunit B, putative
— OG7
TcCLB.506405.120 ⚠
V-type ATPase, A subunit, putative
— OG7
TcCLB.511731.80 ⚠
Mitochondrial small ribosomal subunit mS56, p
— OG7
TcCLB.511067.10 ⚠
tubulin folding cofactor D, putative
— OG7
TcCLB.508717.40 ⚠
branch point binding protein, putative
— OG7
TcCLB.509007.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508181.20 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506733.60 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
TcCLB.503975.100 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcCLB.509979.40 ⚠
Zn-finger in Ran binding protein and others/S
— OG7
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.507925.69 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508781.110 ⚠
2-oxoisovalerate dehydrogenase alpha subunit,
— OG7
TcCLB.508387.30 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.504203.50 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.506857.110 ⚠
Uncharacterised protein family UPF0066, putat
— OG7
TcCLB.503893.140 ⚠
zinc-finger of a C2HC-type, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.