TcCLB.509979.40

Zn-finger in Ran binding protein and others/SPRY domain/HECT-domain (ubiquitin-transferase), putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_146743 OG7: OG7_0043053 211 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 211 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511627.140
hypothetical protein, conserved
— Both
TcCLB.510257.130 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.421959.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.510525.10 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.504935.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.506677.10 ⚠
ubiquitin-like protein, putative
— OG7
TcCLB.504089.54 ⚠
ULK family serine/threonine-protein kinase, p
— OG7
TcCLB.510431.140 ⚠
dual specificity tyrosine-phosphorylation-reg
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.29 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.511627.120
aldo/keto reductase, putative
— OG7
TcCLB.504883.60
hypothetical protein, conserved
— OG7
TcCLB.507993.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.511131.80
hypothetical protein, conserved
— OG7
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.508307.44
pre-mRNA splicing factor 46, putative
— Both
TcCLB.506811.150
hypothetical protein, conserved
— Both
TcCLB.511801.50
tRNA threonylcarbamoyl adenosine modification
— Both
TcCLB.509953.9 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcCLB.506529.490
hypothetical protein, conserved
— Both
TcCLB.511115.40 ⚠
transcription elongation factor s-II, putativ
— Both
TcCLB.511751.200
epsilon-adaptin, putative, AP-1/4 adapter com
— Both
TcCLB.510089.200
Eukaryotic translation initiation factor 3 su
— Both
TcCLB.405165.19 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.506405.10
phosphomannomutase-like protein, putative
— Both
TcCLB.507747.110 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.510405.9 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.508389.130 ⚠
Mucin-associated surface protein (MASP), subg
— OG6
TcCLB.508265.110 ⚠
hypothetical protein, conserved
— Both
TcCLB.510323.20
Flagellum attachment zone protein 19, putativ
— Both
TcCLB.507739.110 ⚠
myosin IB heavy chain, putative
— Both
TcCLB.506943.160
eukaryotic translation initiation factor 3 su
— Both
TcCLB.509167.180
kinesin, putative
— OG6
TcCLB.511109.30 ⚠
dynein intermediate chain, putative
— Both
TcCLB.507671.30
25 kDa translation elongation factor 1-beta
— Both
TcCLB.511211.20
Coatomer subunit gamma
— Both
TcCLB.508321.40
Tripartite attachment complex protein 102
— Both
TcCLB.507611.310
eukaryotic translation initiation factor 3 su
— Both
TcCLB.511577.40
35 kDa cyclophilin, putative, rotamase, putat
— OG6
TcCLB.507611.340
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.