TcCLB.506943.160

eukaryotic translation initiation factor 3 subunit d
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102252 OG7: OG7_0006808 45 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 45 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511303.60
eukaryotic translation initiation factor 3 su
— +2 more Both
TcCLB.507611.310
eukaryotic translation initiation factor 3 su
— Both
TcCLB.508357.100 ⚠
Serine-threonine kinase receptor-associated p
— OG7
TcCLB.511589.230 ⚠
eukaryotic translation initiation factor 3 su
— Both
TcCLB.508169.90
eukaryotic translation initiation factor 3 su
— Both
TcCLB.510877.150
eukaryotic translation initiation factor 3 su
— OG6
TcCLB.509205.30
Eukaryotic translation initiation factor 3 su
— Both
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.506963.10
60S ribosomal protein L10a, putative
— Both
TcCLB.510243.40 ⚠
60S ribosomal protein L10, putative
— Both
TcCLB.510089.200
Eukaryotic translation initiation factor 3 su
— Both
TcCLB.509979.40
Zn-finger in Ran binding protein and others/S
— Both
TcCLB.504883.60
hypothetical protein, conserved
— OG7
TcCLB.506211.70 ⚠
RNA-binding protein, putative
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— Both
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507093.72
repressor activator protein 1
— OG7
TcCLB.506735.70
hypothetical protein, conserved
— OG7
TcCLB.510533.170
hypothetical protein, conserved
— OG7
TcCLB.506147.150 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcCLB.508277.160 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
TcCLB.511001.130
hypothetical protein, conserved
— OG7
TcCLB.504427.140
hypothetical protein, conserved
— Both
TcCLB.509805.170 ⚠
pre-RNA processing PIH1/Nop17, putative
— Both
TcCLB.511211.20
Coatomer subunit gamma
— Both
TcCLB.509073.90
CS domain/TPR repeat, putative
— Both
TcCLB.509267.40
eukaryotic translation initiation factor 3 su
— Both
TcCLB.508321.40
Tripartite attachment complex protein 102
— Both
TcCLB.507671.30
25 kDa translation elongation factor 1-beta
— Both
TcCLB.509167.180
kinesin, putative
— OG6
TcCLB.511731.60 ⚠
glutamyl-tRNA synthetase, putative
— Both
TcCLB.507975.80
eukaryotic translation initiation factor 3 su
— Both
TcCLB.408345.20 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— Both
TcCLB.508515.20
Eukaryotic translation initiation factor 1, p
— Both
TcCLB.510717.30 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— Both
TcCLB.506211.60 ⚠
RNA-binding protein, putative
— Both
TcCLB.503715.10
splicing factor TSR1, putative
— Both
TcCLB.504163.110
n-alpha-acetyltransferase 15, NatA auxiliary
— Both
TcCLB.504119.10
eukaryotic translation initiation factor 5, p
— Both
TcCLB.510241.50 ⚠
60S ribosomal protein L10, putative
— Both
TcCLB.503793.10 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.