TcCLB.408345.20

2-oxoglutarate dehydrogenase subunit, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100311 OG7: OG7_0003220 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511145.46 ⚠
60S ribosomal protein L37a, putative
— Both
TcCLB.511051.39 ⚠
40S ribosomal protein S4, putative
— Both
TcCLB.511051.50 ⚠
40S ribosomal protein S4, putative
— Both
TcCLB.506943.160 ⚠
eukaryotic translation initiation factor 3 su
— Both
TcCLB.430605.29 ⚠
40S ribosomal protein S3, putative
— Both
TcCLB.507677.39 ⚠
40S ribosomal protein S3, putative
— Both
TcCLB.511329.10 ⚠
Calpain-like protein 2
— OG6
TcCLB.477983.10 ⚠
calpain cysteine peptidase, putative
— OG6
TcCLB.506885.14 ⚠
ribosomal protein L37, putative
— Both
TcCLB.510431.274 ⚠
60S ribosomal protein L37, putative
— Both
TcCLB.506937.30 ⚠
60S ribosomal protein L14, putative
— Both
TcCLB.506861.30 ⚠
60S ribosomal protein L14, putative
— Both
TcCLB.503757.10 ⚠
40S ribosomal protein SA, putative
— Both
TcCLB.442383.9 ⚠
40S ribosomal protein SA, putative
— Both
TcCLB.509825.14 ⚠
40S ribosomal protein SA, putative
— Both
TcCLB.507641.233 ⚠
ribosomal protein L37, putative
— Both
TcCLB.506739.150 ⚠
60S ribosomal protein L13a, putative
— Both
TcCLB.510717.30 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— Both
TcCLB.503793.10 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— Both
TcCLB.510565.30 ⚠
cytochrome c oxidase subunit V, putative
— Both
TcCLB.510091.80 ⚠
pyruvate dehydrogenase E1 beta subunit, putat
— Both
TcCLB.509103.10 ⚠
pre-mRNA splicing factor 19, putative
— Both
TcCLB.510105.170 ⚠
dihydrolipoamide acetyltransferase precursor,
— OG7
TcCLB.506211.70 ⚠
RNA-binding protein, putative
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507993.130 ⚠
60S ribosomal protein L7, putative
— OG7
TcCLB.503715.10 ⚠
splicing factor TSR1, putative
— Both
TcCLB.484311.10 ⚠
calpain-like cysteine peptidase, putative (fr
— Both
TcCLB.445281.9 ⚠
calpain-like cysteine peptidase, putative
— Both
TcCLB.511441.10 ⚠
cysteine peptidase, Clan CA, family C2, putat
— Both
TcCLB.511445.10 ⚠
cysteine peptidase, Clan CA, family C2, putat
— Both
TcCLB.511441.20 ⚠
calpain-like cysteine peptidase, putative (fr
— Both
TcCLB.509013.19 ⚠
calpain-like cysteine peptidase, putative (fr
— Both
TcCLB.509013.10 ⚠
calpain-like cysteine peptidase, putative
— Both
TcCLB.507795.10 ⚠
membrane associated protein, putative
— Both
TcCLB.508207.100 ⚠
60S ribosomal protein L7, putative
— Both
TcCLB.508207.110 ⚠
60S ribosomal protein L7, putative
— Both
TcCLB.509103.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.510879.20 ⚠
ribosomal protein S19, putative
— Both
TcCLB.510529.30 ⚠
Mitochondrial small ribosomal subunit mS50, p
— Both
TcCLB.510877.150 ⚠
eukaryotic translation initiation factor 3 su
— OG6
TcCLB.506211.60 ⚠
RNA-binding protein, putative
— Both
TcCLB.504107.10 ⚠
calpain-like cysteine peptidase, putative (fr
— Both
TcCLB.504163.110 ⚠
n-alpha-acetyltransferase 15, NatA auxiliary
— Both
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.