TcCLB.511577.40

35 kDa cyclophilin, putative, rotamase, putative, PPIase, putative, peptidyl-prolyl cis-trans isomerase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_109053 OG7: OG7_0000556 98 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 98 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503991.10
hypothetical protein, conserved
— OG6
TcCLB.503677.10
phosphomannose isomerase, putative
— OG6
TcCLB.503805.10
Mitochondrial Editosome-like Complex TUTase
— OG6
TcCLB.506893.100
UMP-CMP kinase, mitochondrial, putative
— OG6
TcCLB.506405.10
phosphomannomutase-like protein, putative
— OG6
TcCLB.503713.30
6-phosphogluconolactonase, putative
— OG6
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG6
TcCLB.511043.20
small G-protein, putative
— OG6
TcCLB.507993.330
mevalonate-diphosphate decarboxylase, putativ
— OG6
TcCLB.464807.10 ⚠
serine/threonine protein kinase, putative, CA
— OG6
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG6
TcCLB.510311.90
quinone oxidoreductase, putative
— OG6
TcCLB.506407.60 ⚠
CS domain containing protein, putative
— OG6
TcCLB.503991.39
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG6
TcCLB.510143.40
UBX domain-containing protein
— OG6
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG6
TcCLB.503959.78
hypothetical protein, conserved
— OG6
TcCLB.504055.60
hypothetical protein, conserved
— OG6
TcCLB.506925.319 ⚠
isocitrate dehydrogenase, putative
— OG6
TcCLB.509979.40
Zn-finger in Ran binding protein and others/S
— OG6
TcCLB.507165.59
Protein of unknown function (DUF2009), putati
— OG6
TcCLB.507993.390
pyruvate kinase 2, putative
— OG6
TcCLB.509455.30
TAP42-like family, putative
— OG6
TcCLB.511589.140
PEP mutase, putative, phosphoenolpyruvate mut
— OG6
TcCLB.510861.140 ⚠
CAMK/CAMKL family protein kinase, putative
— OG6
TcCLB.511573.40
Mitogen-activated protein kinase 10, putative
— OG6
TcCLB.504147.30
Protein of unknown function (DUF2870), putati
— OG6
TcCLB.509551.70 ⚠
Co-chaperone protein P23
— OG6
TcCLB.509453.4 ⚠
hypothetical protein, conserved
— OG6
TcCLB.507941.100
hypothetical protein, conserved
— OG6
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG6
TcCLB.503685.30
carnitine/choline acetyltransferase, putative
— OG6
TcCLB.506525.80
N-myristoyl transferase, putative
— OG6
TcCLB.508955.20
hypothetical protein, conserved
— OG6
TcCLB.507993.150
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
TcCLB.506591.20
U-box domain protein, putative
— OG6
TcCLB.508373.20 ⚠
dihydroorotase, putative
— OG6
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG6
TcCLB.511575.60 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG6
TcCLB.508347.130
deoxyhypusine hydroxylase, putative
— OG6
TcCLB.507809.60
hypothetical protein, conserved
— OG6
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— OG6
TcCLB.504159.70
hypothetical protein, conserved
— OG6
TcCLB.506363.150 ⚠
soluble N-ethylmaleimide sensitive factor (NS
— OG6
TcCLB.511529.160 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG6
TcCLB.511529.170 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG6
TcCLB.506359.60
UTP-glucose-1-phosphate uridylyltransferase 2
— OG6
TcCLB.506677.39
Elongation factor G1, mitochondrial, putative
— OG6
TcCLB.503893.60
UBA/TS-N domain containing protein, putative
— OG6
TcCLB.507585.10 ⚠
amino acid transporter, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.