TcCLB.511043.20

small G-protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_105709 OG7: OG7_0000131 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507993.150
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
TcCLB.504159.70
hypothetical protein, conserved
— OG6
TcCLB.510311.90
quinone oxidoreductase, putative
— OG6
TcCLB.503477.20
transaldolase, putative
— OG6
TcCLB.508085.10
GMP synthase, putative
— OG6
TcCLB.504147.30
Protein of unknown function (DUF2870), putati
— OG6
TcCLB.509551.70 ⚠
Co-chaperone protein P23
— OG6
TcCLB.509453.4 ⚠
hypothetical protein, conserved
— OG6
TcCLB.507941.100
hypothetical protein, conserved
— OG6
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG6
TcCLB.506525.80
N-myristoyl transferase, putative
— OG6
TcCLB.508955.20
hypothetical protein, conserved
— OG6
TcCLB.510025.170 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.506591.20
U-box domain protein, putative
— OG6
TcCLB.508373.20 ⚠
dihydroorotase, putative
— OG6
TcCLB.511573.40
Mitogen-activated protein kinase 10, putative
— OG6
TcCLB.511575.60 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG6
TcCLB.507809.60
hypothetical protein, conserved
— OG6
TcCLB.511529.160 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG6
TcCLB.511529.170 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG6
TcCLB.506359.60
UTP-glucose-1-phosphate uridylyltransferase 2
— OG6
TcCLB.506677.39
Elongation factor G1, mitochondrial, putative
— OG6
TcCLB.503893.60
UBA/TS-N domain containing protein, putative
— OG6
TcCLB.503991.39
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG6
TcCLB.506931.10
haloacid dehalogenase-like hydrolase, putativ
— OG6
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— OG6
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— OG6
TcCLB.511577.40
35 kDa cyclophilin, putative, rotamase, putat
— OG6
TcCLB.511801.50
tRNA threonylcarbamoyl adenosine modification
— OG6
TcCLB.510323.20
Flagellum attachment zone protein 19, putativ
— OG6
TcCLB.506405.10
phosphomannomutase-like protein, putative
— OG6
TcCLB.511751.200
epsilon-adaptin, putative, AP-1/4 adapter com
— OG6
TcCLB.511115.40
transcription elongation factor s-II, putativ
— OG6
TcCLB.509953.9 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG6
TcCLB.509955.10 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG6
TcCLB.503841.70
aspartate aminotransferase, putative
— OG6
TcCLB.503805.10
Mitochondrial Editosome-like Complex TUTase
— OG6
TcCLB.511741.40
RNA-binding protein, putative
— OG6
TcCLB.511693.90
electron-transfer-flavoprotein, alpha polypep
— OG6
TcCLB.509767.90
alanine racemase, putative
— OG6
TcCLB.511693.70
hypothetical protein, conserved
— OG6
TcCLB.511711.50
hypothetical protein, conserved
— OG6
TcCLB.503685.30
carnitine/choline acetyltransferase, putative
— OG6
TcCLB.503959.78
hypothetical protein, conserved
— OG6
TcCLB.507641.80 ⚠
5'-3' exoribonuclease D, putative
— OG6
TcCLB.506351.9 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG6
TcCLB.507817.80 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG6
TcCLB.509965.330 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506747.20 ⚠
dihydroorotase, putative
— OG6
TcCLB.506795.44
Bifunctional NAD(P)H-hydrate repair enzyme
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.