TcCLB.503677.10

phosphomannose isomerase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102059 OG7: OG7_0006704 162 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 162 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506949.20
hypothetical protein, conserved
— Both
TcCLB.504125.60 ⚠
Kinesin-13 3, putative
— Both
TcCLB.507585.10 ⚠
amino acid transporter, putative
— OG6
TcCLB.511741.50 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
TcCLB.511543.30 ⚠
amino acid permease, putative, amino acid tra
— OG6
TcCLB.508207.240 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
TcCLB.508085.10
GMP synthase, putative
— Both
TcCLB.503477.20
transaldolase, putative
— Both
TcCLB.509965.380 ⚠
dTDP-glucose 4,6-dehydratase, putative
— Both
TcCLB.504159.70
hypothetical protein, conserved
— Both
TcCLB.510025.170 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.507817.80 ⚠
5'-3' exoribonuclease A, putative (fragment)
— Both
TcCLB.506351.9 ⚠
5'-3' exoribonuclease A, putative (fragment)
— Both
TcCLB.507641.80 ⚠
5'-3' exoribonuclease D, putative
— Both
TcCLB.510747.100
hypothetical protein, conserved
— Both
TcCLB.511871.30 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
TcCLB.511711.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.511693.70
hypothetical protein, conserved
— Both
TcCLB.511693.90
electron-transfer-flavoprotein, alpha polypep
— Both
TcCLB.509767.90
alanine racemase, putative
— Both
TcCLB.511741.40
RNA-binding protein, putative
— OG6
TcCLB.506931.10 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcCLB.503841.70
aspartate aminotransferase, putative
— Both
TcCLB.509955.10 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcCLB.509953.9 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcCLB.511115.40 ⚠
transcription elongation factor s-II, putativ
— Both
TcCLB.511751.200
epsilon-adaptin, putative, AP-1/4 adapter com
— Both
TcCLB.506405.10
phosphomannomutase-like protein, putative
— Both
TcCLB.511801.50
tRNA threonylcarbamoyl adenosine modification
— Both
TcCLB.511577.40
35 kDa cyclophilin, putative, rotamase, putat
— OG6
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.507993.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511627.120
aldo/keto reductase, putative
— OG7
TcCLB.510777.29 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.511419.50 ⚠
3-phosphoglycerate kinase, glycosomal
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510939.9 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511001.60 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.511801.14 ⚠
protein lipid droplet kinase (LDK)
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511145.80 ⚠
RNA polymerase II, putative
— OG7
TcCLB.506493.50 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.