TcCLB.511145.80

RNA polymerase II, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_141860 OG7: OG7_0002307 131 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 131 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509199.10 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TcCLB.506525.80 ⚠
N-myristoyl transferase, putative
— OG7
TcCLB.503959.78 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.29 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.407477.30 ⚠
diphthine synthase, putative
— OG7
TcCLB.503841.70 ⚠
aspartate aminotransferase, putative
— OG7
TcCLB.504935.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.506127.170 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcCLB.421959.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.503893.60 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcCLB.506677.10 ⚠
ubiquitin-like protein, putative
— OG7
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.506691.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509203.30 ⚠
hd phosphohydrolase family protein
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.503713.30 ⚠
6-phosphogluconolactonase, putative
— OG7
TcCLB.506677.39 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
TcCLB.510525.10 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.511911.130 ⚠
phosphoglucomutase
— OG7
TcCLB.506795.44 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
TcCLB.510719.60 ⚠
Biotin--acetyl-CoA-carboxylase ligase, putati
— OG7
TcCLB.506747.20 ⚠
dihydroorotase, putative
— OG7
TcCLB.510257.130 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.506635.60 ⚠
pyroglutamyl-peptidase I, putative
— OG7
TcCLB.509205.110 ⚠
elongation factor G2-like protein, putative
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.503991.39 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
TcCLB.506591.20 ⚠
U-box domain protein, putative
— OG7
TcCLB.511001.60 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506493.50 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcCLB.507941.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506495.3 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508955.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507993.330 ⚠
mevalonate-diphosphate decarboxylase, putativ
— OG7
TcCLB.511577.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511115.40 ⚠
transcription elongation factor s-II, putativ
— OG7
TcCLB.507669.100 ⚠
transcription elongation factor, putative
— OG7
TcCLB.508207.240 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
TcCLB.511693.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508727.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508373.20 ⚠
dihydroorotase, putative
— OG7
TcCLB.510595.20 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.