TcCLB.506375.60

tryptophanyl-tRNA synthetase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_137983 OG7: OG7_0005676 137 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 137 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510719.310 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511049.40 ⚠
leucyl-tRNA synthetase, putative
— OG7
TcCLB.510997.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.505843.40 ⚠
E1-like ubiquitin-activating enzyme, putative
— OG7
TcCLB.506925.260 ⚠
Atypical serine/threonine protein kinase BUD3
— OG7
TcCLB.506945.80 ⚠
DNA ligase I, putative
— OG7
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— OG7
TcCLB.511555.80 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcCLB.507993.260 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510599.30 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
TcCLB.510283.70 ⚠
glycosyl hydrolase-like protein, putative
— OG7
TcCLB.506733.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503637.30 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.503487.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.510963.39 ⚠
PUB domain containing protein, putative
— OG7
TcCLB.509551.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511741.50 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
TcCLB.399033.19 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
TcCLB.508463.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509123.30 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
TcCLB.510321.20 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.509805.40 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcCLB.506699.3 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.511307.6 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.503653.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— OG7
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— OG7
TcCLB.507735.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506409.240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, C-t
— OG7
TcCLB.507677.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.504137.80 ⚠
adenylyl cyclase-associated protein, putative
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.510181.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503671.30 ⚠
leucine-rich repeat-containing protein
— OG7
TcCLB.510533.120 ⚠
translation initiation factor IF-2, putative
— OG7
TcCLB.506405.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504119.29 ⚠
deoxyhypusine synthase, putative
— OG7
TcCLB.511421.60 ⚠
deoxyhypusine synthase, putative
— OG7
TcCLB.508089.30 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
TcCLB.509669.90 ⚠
XPC-binding domain/UBA/TS-N domain containing
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.