TcCLB.504137.80

adenylyl cyclase-associated protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101374 OG7: OG7_0005390 74 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 74 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510743.100 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.510231.20
hypothetical protein
— OG7
TcCLB.507257.180 ⚠
hypothetical protein
— OG7
TcCLB.511531.9 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.510165.10 ⚠
heat shock protein DNAJ, putative
— OG7
TcCLB.508179.10 ⚠
DnaJ chaperone protein, putative
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.510241.70 ⚠
heat shock protein, putative
— OG7
TcCLB.509233.80 ⚠
heat shock protein DNAJ, putative
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— OG7
TcCLB.504867.20
ABC transporter, putative
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.507713.30 ⚠
heat shock protein 85, putative
— OG7
TcCLB.506591.4 ⚠
heat shock protein 90, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.507713.40 ⚠
heat shock protein 85, putative (fragment)
— OG7
TcCLB.508277.160 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
TcCLB.506733.140
hypothetical protein, conserved
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.510719.310
hypothetical protein, conserved
— Both
TcCLB.507735.10
hypothetical protein, conserved
— Both
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— Both
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— Both
TcCLB.504213.20
Protein of unknown function (DUF1253), putati
— Both
TcCLB.506659.30
glutathione synthetase, putative
— Both
TcCLB.508469.59
helicase, putative
— OG6
TcCLB.506777.60
NGG1 interacting factor 3, putative
— Both
TcCLB.505843.40
E1-like ubiquitin-activating enzyme, putative
— Both
TcCLB.508321.30
hypothetical protein, conserved
— OG6
TcCLB.503653.20
hypothetical protein, conserved
— Both
TcCLB.509125.20 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
TcCLB.508807.10 ⚠
atp-dependent chaperone, ATP-dependent Clp pr
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.