TcCLB.507735.10

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102942 OG7: OG7_0008031 92 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 92 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506517.149 ⚠
Acyl CoA binding protein, putative
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.510231.20
hypothetical protein
— OG7
TcCLB.504867.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506265.160
hypothetical protein, conserved
— OG7
TcCLB.510609.30 ⚠
GTPase, putative
— OG7
TcCLB.506287.150 ⚠
GTP-binding protein, putative
— OG7
TcCLB.504153.300 ⚠
GTPase protein, putative
— OG7
TcCLB.506127.20 ⚠
mRNA export factor MEX67
— OG7
TcCLB.504153.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508271.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510249.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.511369.10 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.506953.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508949.4 ⚠
elongation factor 1-alpha (ef-1-alpha), putat
— OG7
TcCLB.511369.20 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.511369.30 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.510877.55 ⚠
acyl-CoA binding protein, putative
— OG7
TcCLB.511369.5 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— OG7
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— Both
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcCLB.506925.10 ⚠
hypothetical protein
— OG7
TcCLB.511911.71 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.506211.150
polyprenyl synthase, putative
— OG7
TcCLB.511041.50
flagellum transition zone component, putative
— OG7
TcCLB.503551.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508385.30 ⚠
CYC2-like cyclin, putative
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506945.270 ⚠
cyclin, putative
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.506363.70 ⚠
amidohydrolase, putative
— Both
TcCLB.417091.10 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.506625.249 ⚠
RNA pseudouridylate synthase protein, putativ
— OG7
TcCLB.506925.260
Atypical serine/threonine protein kinase BUD3
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511303.30
methyltransferase domain containing protein,
— Both
TcCLB.504213.20
Protein of unknown function (DUF1253), putati
— Both
TcCLB.511585.40
DNA-damage inducible protein DDI1-like protei
— Both
TcCLB.508271.30 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.