TcCLB.510249.14

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_153964 OG7: OG7_0002395 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506239.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506135.90 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.503579.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508385.30 ⚠
CYC2-like cyclin, putative
— OG7
TcCLB.506227.230 ⚠
N-alpha-acetyltransferase 10, NatA catalytic
— OG7
TcCLB.510777.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506127.20 ⚠
mRNA export factor MEX67
— OG7
TcCLB.504883.50 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— OG7
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— OG7
TcCLB.510603.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511313.20 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
TcCLB.509167.170 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
TcCLB.503551.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506743.170 ⚠
Met-10+ like-protein, putative
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.507735.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508271.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.417091.10 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.511303.30 ⚠
methyltransferase domain containing protein,
— OG7
TcCLB.510243.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504153.300 ⚠
GTPase protein, putative
— OG7
TcCLB.506287.150 ⚠
GTP-binding protein, putative
— OG7
TcCLB.510351.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510609.30 ⚠
GTPase, putative
— OG7
TcCLB.511585.40 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcCLB.504153.160 ⚠
Metallocarboxypeptidase 1
— OG7
TcCLB.506825.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506265.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506181.150 ⚠
hypothetical protein (fragment)
— OG7
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.506127.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506925.260 ⚠
Atypical serine/threonine protein kinase BUD3
— OG7
TcCLB.506363.90 ⚠
amidohydrolase, putative
— OG7
TcCLB.506363.70 ⚠
amidohydrolase, putative
— OG7
TcCLB.511041.50 ⚠
flagellum transition zone component, putative
— OG7
TcCLB.506211.150 ⚠
polyprenyl synthase, putative
— OG7
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506925.10 ⚠
hypothetical protein
— OG7
TcCLB.508271.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507047.80 ⚠
zinc-finger protein ZPR1, putative
— OG7
TcCLB.504153.140 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.503885.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— OG7
TcCLB.510101.140 ⚠
pyruvate phosphate dikinase, putative
— OG7
TcCLB.509551.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511751.210 ⚠
phosphopantothenoylcysteine decarboxylase, pu
— OG7
TcCLB.506625.249 ⚠
RNA pseudouridylate synthase protein, putativ
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.