TcCLB.506779.50

proteasome beta 3 subunit, putative

Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101970 OG7: OG7_0007205 41 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 41 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcCLB.506885.350 ⚠ proteasome alpha 1 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.9.9670 OG6 LdBPK_280110.1 ↔ LdBPK_354910.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_005678 OG7 Tb927.11.7020 ↔ Tb927.11.7270 +19 more	Both
TcCLB.416883.18 ⚠ proteasome alpha 2 subunit, putative	—	OG6 Tb927.10.290 ↔ Tb927.11.7270 OG6 LdBPK_212070.1 ↔ LdBPK_280110.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_009369 OG7 Tb927.11.7020 ↔ Tb927.11.7270 +19 more	Both
TcCLB.507639.40 ⚠ proteasome subunit beta type-5, putative	—	OG6 Tb927.10.6080 ↔ Tb927.11.7270 OG6 LdBPK_280110.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_280110.1 OG7 LdBPK_280110.1 ↔ LdBPK_353880.1 +5 more	Both
TcCLB.511145.43 ⚠ proteasome subunit alpha type-5, putative	—	OG6 Tb927.10.230 ↔ Tb927.11.7270 OG6 LdBPK_212200.1 ↔ LdBPK_280110.1 OG7 Tb927.11.7020 ↔ Tb927.11.7270 OG7 Tb927.10.230 ↔ Tb927.11.7270 +18 more	Both
TcCLB.506167.40 ⚠ proteasome subunit alpha type-1, putative	—	OG6 Tb11.v5.0196 ↔ Tb927.11.7270 OG6 Tb927.10.6030 ↔ Tb927.11.7270 OG6 LdBPK_280110.1 ↔ LdBPK_361670.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004937 +20 more	Both
TcCLB.503613.20 ⚠ proteasome alpha 7 subunit, putative	—	OG6 LdBPK_110240.1 ↔ LdBPK_280110.1 OG6 Tb927.11.7020 ↔ Tb927.11.7270 OG6 TCSYLVIO_001707 ↔ TCSYLVIO_001736 OG7 Tb927.11.7020 ↔ Tb927.11.7270 +19 more	Both
TcCLB.507603.40 ⚠ proteasome beta-1 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.6.1260 OG6 LdBPK_120030.1 ↔ LdBPK_280110.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_006999 OG7 LdBPK_120030.1 ↔ LdBPK_280110.1 +6 more	Both
TcCLB.504213.120 ⚠ proteasome alpha 3 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.7.4420 OG6 LdBPK_140310.1 ↔ LdBPK_280110.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010341 OG7 Tb927.11.7020 ↔ Tb927.11.7270 +19 more	Both
TcCLB.511867.50 ⚠ proteasome alpha 7 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.3.780 OG6 LdBPK_270190.1 ↔ LdBPK_280110.1 OG7 Tb927.11.7020 ↔ Tb927.11.7270 OG7 Tb927.10.230 ↔ Tb927.11.7270 +18 more	Both
TcCLB.507521.50 proteasome beta 6 subunit, putative, 20S prot	—	OG6 Tb927.11.7270 ↔ Tb927.7.4790 OG6 LdBPK_060140.1 ↔ LdBPK_280110.1 OG7 Tb927.11.7270 ↔ Tb927.7.4790 OG7 LdBPK_060140.1 ↔ LdBPK_280110.1	Both
TcCLB.510287.30 proteasome subunit beta type-2, putative	—	OG6 LdBPK_280110.1 ↔ LdBPK_360340.1 OG6 Tb927.10.4710 ↔ Tb927.11.7270 OG7 LdBPK_280110.1 ↔ LdBPK_360340.1 OG7 Tb927.10.4710 ↔ Tb927.11.7270	Both
TcCLB.510105.9 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004479	OG7
TcCLB.510431.250 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004731	Both
TcCLB.430737.20 ⚠ hypothetical protein, conserved (fragment)	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010606	Both
TcCLB.504057.110 exosome complex exonuclease, putative, riboso	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_003804 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_003804	Both
TcCLB.510599.14 ⚠ acetyl-CoA carboxylase (fragment)	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_002772 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_002772	Both
TcCLB.503777.19 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004731	Both
TcCLB.507089.80 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_001893	Both
TcCLB.504181.50 ⚠ T-complex protein 1, delta subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	Both
TcCLB.506863.50 ⚠ ribosomal RNA processing protein 45, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_001893	Both
TcCLB.508717.30 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004731	Both
TcCLB.511531.40 ⚠ chaperonin alpha subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	Both
TcCLB.506691.14 ⚠ ATP-dependent DEAD/H RNA helicase, putative (	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004479 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004479	Both
TcCLB.509583.10 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	OG7
TcCLB.508357.90 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	OG7
TcCLB.507809.30 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004731	OG7
TcCLB.504119.10 eukaryotic translation initiation factor 5, p	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004556	Both
TcCLB.510313.20 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004479 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004479	Both
TcCLB.506607.19 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004731	Both
TcCLB.506795.90 ⚠ 'Cold-shock' DNA-binding domain containing pr	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010606	Both
TcCLB.468941.9 ⚠ ATP-dependent DEAD/H RNA helicase, putative (	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004479 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004479	Both
TcCLB.508369.50 ⚠ acetyl-CoA carboxylase (fragment)	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_002772 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_002772	Both
TcCLB.504867.40 acetyltransferase, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004519 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004519	Both
TcCLB.510557.50 ⚠ mucin TcMUCII, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_002772	OG6
TcCLB.508469.59 helicase, putative	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_001736	OG6
TcCLB.510515.139 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	Both
TcCLB.510517.10 ⚠ chaperonin/T-complex protein 1 gamma subunit,	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	Both
TcCLB.506775.180 hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_001736	Both
TcCLB.511621.180 ⚠ Phosducin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_001736	Both
TcCLB.509069.20 ⚠ ATP binding protein-like protein, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_001736	Both
TcCLB.509073.119 proteasome regulatory non-ATP-ase subunit 7,	—	OG6 Tb927.11.16030 ↔ Tb927.11.7270 OG7 Tb927.11.16030 ↔ Tb927.11.7270	Both