TcCLB.504427.50

5'-AMP-activated protein kinase subunit beta, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101253 OG7: OG7_0004018 91 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 91 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510243.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508557.29 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcCLB.510747.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507093.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506289.70
hypothetical protein, conserved
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.509835.10 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.504159.60
hypothetical protein, conserved
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.508465.60
hypothetical protein, conserved
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504087.10 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506563.10 ⚠
pumilio/PUF RNA binding protein 9, putative
— OG7
TcCLB.509759.19 ⚠
pumilio/PUF RNA binding protein 1, putative
— OG7
TcCLB.510073.30 ⚠
pumilio/PUF RNA binding protein 4, putative
— OG7
TcCLB.508787.30 ⚠
pumilio/PUF RNA binding protein 3, putative
— OG7
TcCLB.507521.110 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510105.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.510609.130
hypothetical protein, conserved
— OG7
TcCLB.507797.9 ⚠
nuclear transcription factor, putative
— OG7
TcCLB.506493.50 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcCLB.511001.60 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.511801.14 ⚠
protein lipid droplet kinase (LDK)
— OG7
TcCLB.464807.10 ⚠
serine/threonine protein kinase, putative, CA
— OG7
TcCLB.510861.140 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.510257.130 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.510525.10 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.506513.24 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.397937.10 ⚠
pumilio/PUF RNA binding protein 1, putative
— OG7
TcCLB.510749.4 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.508277.190 ⚠
ERAD-associated E3 ubiquitin-protein ligase H
— OG7
TcCLB.508779.40 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.511127.250 ⚠
hypothetical protein, conserved
— OG7
TcCLB.430539.10 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.511467.16 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510349.30
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.508183.4
aspartyl aminopeptidase, putative (fragment)
— Both
TcCLB.510769.70 ⚠
hypothetical protein
— Both
TcCLB.504423.30
hypothetical protein, conserved
— Both
TcCLB.506237.19 ⚠
hypothetical protein, conserved
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.